Results 51 to 60 of about 778,284 (301)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Efficient minimum blind area model for system and interference uncertainty

IET Microwaves, Antennas & Propagation
In the anti‐interference of broadband communication radio, interference cancellation performance is seriously affected by the uncertainty of the working frequency selection of the communication system and the direction of hostile interference. The closed‐
Yu Guo, Songhu Ge, Jin Meng
doaj   +1 more source

The Murchison Widefield Array: the Square Kilometre Array Precursor at low radio frequencies [PDF]

, 2012
The Murchison Widefield Array (MWA) is one of three Square Kilometre Array Precursor telescopes and is located at the Murchison Radio-astronomy Observatory in the Murchison Shire of the mid-west of Western Australia, a location chosen for its extremely ...
A. Deshpande, A. E. E. Rogers, A. R. Whitney, A. Roshi, A. Wicenec, A. Williams, B. B. Kincaid, B. Crosse, B. E. Corey, B. J. Hazelton, B. M. Gaensler, B. Mckinley, Bernardi, Bhatnagar, Bowman, Bracewell, C. J. Lonsdale, C. L. Williams, Cornwell, Cornwell, D. A. Mitchell, D. Barnes, D. Emrich, D. Herne, D. L. Kaplan, D. Oberoi, D. Pallot, E. Kratzenberg, E. Morgan, Erickson, F. Briggs, F. Schlagenhaufer, Fender, G. Bernardi, Hamaker, J. C. Kasper, J. D. Bowman, J. D. Bunton, J. E. Salah, J. N. Hewitt, J. Pathikulangara, J. S. B. Wyithe, J. Stevens, Johnston, K. S. Srivani, L. Desouza, L. J. Greenhill, M. F. Morales, M. J. Lynch, M. Johnston-Hollitt, M. Waterson, McKinley, N. Kudryavtseva, N. Udaya-Shankar, P. J. Hall, Perley, R. A. Remillard, R. B. Wayth, R. Goeke, R. J. Cappallo, R. J. Sault, R. Koenig, R. L. Webster, R. Subrahmanyan, S. Burns, S. J. Tingay, S. M. Ord, S. R. Mcwhirter, S. Tremblay, Smirnov, T. Booler, T. Colegate, T. Prabu, W. Arcus, Wells, Wicenec   +75 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Electromagnetic Lens-focusing Antenna Enabled Massive MIMO: Performance Improvement and Cost Reduction [PDF]

, 2014
Massive multiple-input multiple-output (MIMO) techniques have been recently advanced to tremendously improve the performance of wireless communication networks.
Chen, Zhi Ning, Zeng, Yong, Zhang, Rui
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Assessment of Measurement Distortions in GNSS Antenna Array Space-Time Processing

International Journal of Antennas and Propagation, 2016
Antenna array processing techniques are studied in GNSS as effective tools to mitigate interference in spatial and spatiotemporal domains. However, without specific considerations, the array processing results in biases and distortions in the cross ...
Thyagaraja Marathe, Saeed Daneshmand, Gérard Lachapelle   +2 more
doaj   +1 more source