Results 91 to 100 of about 705,460 (317)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

[Arrest Report on Investigative Prisoner Jack Ruby #3]

, 1963
Arrest Report on Jack Ruby on the shooting of Lee Harvey Oswald, by J. W. Fritz.
Fritz, J. W.
core  

Data From: The Earthquake Arrest Zone

, 2020
Please note the zipped data file is approximately 1.7GB in size and may take a long time to download.These data are from Laboratory Earthquake Experiments from the Cornell 3 m apparatus in support of the following research: Loading a 3-meter granite slab
Ke, Chun-Yu, McLaskey, Gregory C., Kammer, David S.   +2 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Удосконалення практики застосування й виконання покарання у виді арешту шляхом внесення змін до КК України

Проблеми Законності, 2013
Проаналізовано основні проблеми Кримінального кодексу України (2001 р.) в аспекті вдосконалення практики застосування та виконання покарання у виді арешту. Запропоновано нові редакції статей 391, 392, 393 закону.
К. А. Автухов
doaj   +1 more source

HPV-18 transformed cells fail to arrest in G1 in response to quercetin treatment [PDF]

, 2005
Previous work with primary human keratinocytes demonstrated that quercetin, a potent mutagen found in high levels in bracken fern (Pteridium aquilinum), arrested cells in G1 with concomitant elevation of the cyclin-dependent kinase inhibitor (cdki ...
Beniston, R.G., Campo, M.S.
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

THE PROCEDURES FOR THE COLLECTION OF URINE SAMPLES AND ARREST WITH REGARDS TO DRUG CASES IN MALAYSIA

UUM Journal of Legal Studies, 2022
This research focuses on the position of the relevant procedures concerning an arrest with regards to drug cases in Malaysia. There are three relevant acts that provide for the procedures for arrest concerning drug related cases in Malaysia.
Muhamad Helmi Md. Said, Anusha Asokakumar, Bong Jia Er, Nurul Arwani Zafirah Biamin, Muhammad Khabir Hariz A Rahim, Nurin Athirah Mohd Alam Shah, Awathif Azman   +6 more
doaj  

[Arrest Report on Investigative Prisoner Jack Ruby #1]

, 1963
Arrest Report on Jack Ruby on the shooting of Lee Harvey Oswald, by J. W. Fritz.
Fritz, J. W.
core