Results 71 to 80 of about 705,460 (317)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
, 2012 M.PhilJudicial cooperation is in the fore of European Union (hereinafter referred to as EU) integration in criminal matters. In the past decade we have witnessed revolutionary efforts to introduce new mechanisms in this field that have reshaped EU ...
Defteras, Dora-Maria
core
, 2014 Purpose: The study aims to describe 11 years of experience with extracorporeal cardiopulmonary resuscitation (ECPR) for in-hospital paediatric cardiac arrest in a university affiliated tertiary care hospital.
Huang, Shu-Chien;Wu, En-Ting;Wang, Ching-Chia;Chen, Yih-Sharng;Chang, Chung-I;Chiu, Ing-Sh;Ko, Wen-Je;Wang, Shoei-Shen +1 more
core +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Orthopaedic implications of physeal arrest following meningococcal septicaemia
, 2010 Includes bibliographical references (leaves 45-46).Thirteen patients seen at Red Cross Children's and Maitland Cottage hospitals have under gone complex treatment for the significant deformities caused by meningococcal septicaemia.
Du Plessis, Jean-Pierre
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Clinical Case Reports, 2018 Key Clinical Message Clamshell thoracotomy (CST) may be indicated and life‐saving in carefully selected cases of blunt trauma. As such, the current clinical stance of general contraindication of CST in blunt trauma should be reviewed and criteria ...
Patrick Schober +4 more
doaj +1 more source
Social Sciences, 2015 In 1996, a coordinated community response (CCR) was formally established in a mid-sized Midwestern city to improve the criminal justice response to intimate partner violence (IPV). Data for this study included all IPV-related incidents to which the local
Kerry Beldin +3 more
doaj +1 more source