Results 111 to 120 of about 1,071,960 (344)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Pre-Trial Detention Challenges in Sweden and Ukraine

Journal of Legal Studies
This article conducts a comparative analysis of pre-trial detention challenges in Ukraine and Sweden, highlighting common issues and distinctive features.
Melnykova Dariia
doaj   +1 more source

Emergency clamshell thoracotomy in blunt trauma resuscitation: Shelling the paradigm‐2 cases and review of the literature

Clinical Case Reports, 2018
Key Clinical Message Clamshell thoracotomy (CST) may be indicated and life‐saving in carefully selected cases of blunt trauma. As such, the current clinical stance of general contraindication of CST in blunt trauma should be reviewed and criteria ...
Patrick Schober, Marcel A. de Leeuw, Maartje Terra, Stephan A. Loer, Lothar A. Schwarte   +4 more
doaj   +1 more source

Cardiac Arrest [PDF]

BMJ, 1959
E, THOMAS, K G, WRIGHT
openaire   +2 more sources

Erratum to: Fast track intervention effects on youth arrests and delinquency [PDF]

, 2010
Conduct Problems Prevention Research Group
openalex   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Hapšenje Milivoja Trbića u januaru 1947. [PDF]

Istorija 20. Veka, 2014
This article has an aim to make a reconstruction of the arrest of Milivoj Trbić. He was arrested by the Administration of State Security on January 16, 1947 in the Prilep village Zrze.
Aleksandar Simonovski
doaj  

Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia.

New England Journal of Medicine, 2002
Stephen A Bernard, T. Gray, Michael D. Buist, B. M. Jones, W. Silvester, G. Gutteridge, Karen Smith   +6 more
semanticscholar   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Correction: Development of a Real-Time Risk Prediction Model for In-Hospital Cardiac Arrest in Critically Ill Patients Using Deep Learning: Retrospective Study (Preprint)

, 2020
Yu Rang Park
openalex   +1 more source