Results 61 to 70 of about 1,071,960 (344)

Pediatric Post-Cardiac Arrest Care: A Scientific Statement From the American Heart Association.

Circulation, 2019
Successful resuscitation from cardiac arrest results in a post-cardiac arrest syndrome, which can evolve in the days to weeks after return of sustained circulation.
A. Topjian, A. D. De Caen, M. Wainwright, B. Abella, N. Abend, D. Atkins, M. Bembea, E. Fink, A. Guerguerian, Sarah E. Haskell, J. Kilgannon, J. Lasa, M. Hazinski   +12 more
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Citations and Convictions: One Community’s Coordinated Response to Intimate Partner Violence & Efforts toward Offender Accountability

Social Sciences, 2015
In 1996, a coordinated community response (CCR) was formally established in a mid-sized Midwestern city to improve the criminal justice response to intimate partner violence (IPV). Data for this study included all IPV-related incidents to which the local
Kerry Beldin, Allison Lauritsen, Henry D'Souza, Bob Moyer   +3 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Cardiac Arrest and Cardiopulmonary Resuscitation Outcome Reports: Update of the Utstein Resuscitation Registry Template for In-Hospital Cardiac Arrest: A Consensus Report From a Task Force of the International Liaison Committee on Resuscitation (American Heart Association, European Resuscitation Cou

Circulation, 2019
Utstein-style reporting templates provide a structured framework with which to compare systems of care for cardiac arrest. The 2004 Utstein reporting template encompassed both out-of-hospital and in-hospital cardiac arrest.
J. Nolan, R. Berg, L. Andersen, F. Bhanji, P. Chan, M. Donnino, S. Lim, M. Ma, V. Nadkarni, M. A. Starks, G. Perkins, P. Morley, J. Soar   +12 more
semanticscholar   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The Arrest of Ships in Order to Secure Maritime Claims in Ukraine [PDF]

Lex Portus, 2018
The article defines the problems of current law enforcement practice in the sphere of ship arrests in Ukraine. It also highlights the necessity of forming a unified position of judicial authorities in order to eliminate ambiguous interpretation of legal ...
Sergeyev, Yuriy
doaj   +1 more source

Epithelial to Mesenchymal Transition induces cell cycle arrest and parenchymal damage in renal fibrosis

Nature Medicine, 2015
Kidney fibrosis is marked by an epithelial-to-mesenchymal transition (EMT) of tubular epithelial cells (TECs). Here we find that, during renal fibrosis, TECs acquire a partial EMT program during which they remain associated with their basement membrane ...
S. Lovisa, Valerie S. LeBleu, B. Tampe, H. Sugimoto, Komal Vadnagara, Julienne L. Carstens, Chia-Chin Wu, Y. Hagos, B. Burckhardt, Tsvetelina Pentcheva-Hoang, Hersharan Nischal, J. Allison, M. Zeisberg, R. Kalluri   +13 more
semanticscholar   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Arrestees Substance Abuse: Moving Toward Rehabilitation Camps or Prisons

Iranian Rehabilitation Journal, 2020
Objectives: Illicit drug abuse and drug-related crimes are still a growing problem worldwide. Understanding the increasing number of individuals arrested for drug charges, as well as their characteristics is necessary to predict and establish preventive ...
Fahimeh Mohseni, Elie Moghimi Khorasani, Ali Asghar Nadi Ghara, Raheleh Rafaiee   +3 more
doaj