Results 91 to 100 of about 2,843 (250)
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Combustion arrester quantification systems and methods
Systems and methods for quantifying combustion arrester performance are disclosed. Methods include filling an upstream volume and a combustion arrester with a flammable gas, igniting the flammable gas in the upstream volume (and upstream of the ...
Roberts, William Lafayette +3 more
core
ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley +5 more
wiley +1 more source
Patent for an improved and simplified spark arrester, which deflects sparks and other products of combustion back into the furnace or into a designated ...
Anderson, Oliver Lacy
core
Analisa Peralatan Lightning Arrester pada GIS Teling 150 kV
— Electricity has now become one of the most critical factors in daily life and a primary source in the industry. Gas Insulated Switchgear play a crucial role in the electrical transmission system or power distribution, which is why Gas Insulated ...
Tambingon, Jan James +2 more
core
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Thermal models of a flame arrester [PDF]
"To increase the capability to predict the effectiveness of a flame arrester in the cooling of hot combustion gases expelled through a flame arrester, the U.S.
core
Connecting methods of location monitoring equipment to overhead power lines
THE RELEVANCE of the research lies in expanding the technical capabilities of location monitoring of overhead power lines by developing a method for connecting location equipment to them in the absence of standard high-frequency processing of lines ...
R. G. Minullin +5 more
doaj +1 more source
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source

