Results 81 to 90 of about 381,921 (325)
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Towards a novel design method for impact on leading edges [PDF]
, 2006 Results of a parametric study concerning low velocity impact on leading edge profiles is presented. This work is the first part of a larger program on the development of an engineering design method for impact on Glare.
Houten, M.H. van, Kaplan, H.
core +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
High-Frequency Test of Electric Locomotive Arrester and Its PHM Design
EnergiesThe zinc oxide (ZnO) arrester is positioned on the locomotive roof, preventing other onboard electrical equipment from being harmed by external and internal overvoltages.
Xinping Peng +4 more
doaj +1 more source
Induksi Dan Konduksi Gelombang Elektromagnetik Akibat Sambaran Petir Pada Jaringan Tegangan Rendah [PDF]
, 2009 Induction and Conduction Electromagnetic Waves Caused by Lightning Strike on the Low Voltage Network.Direct and indirect lightning strikes can disturb and induce low voltage overheadlines and it can produced overvoltagedue to traveling waves along the ...
Zoro, R. (Reynaldo)
core
MAKNA SOSIAL NILAI-NILAI KEMANUSIAAN PO-5 BAGI GEN Z SUKU BUTON DI K OTA BAUBAU [PDF]
, 2023 This research aims to examine how the Butonese Z Generation in Baubau City interprets the social meaning of PO-5 Human Values and how to Implement PO-5 Human Values for the Butonese Z Generation in Baubau City.
Rusli, Rusli
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Kajian Pemasangan Lightning Arrester pada Sisi Hv Transformator Daya Unit Satu Gardu Induk Teluk Betung [PDF]
, 2017 Generally, The power centers are connected to the air transmission line, and the airborne transmission channel is susceptible to disturbances that are affected from outside the system, one of which is a lightning strike.
Jurnal, R. T. (Redaksi)
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source