Results 101 to 110 of about 438,424 (336)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Researches on grounding modes of the AC/DC hybrid system with various distributed renewable energy

open access: yesThe Journal of Engineering, 2019
With the considerable demand for distributed renewable energy and the significant increase of generalised DC loads, such as IT equipment, DC air-conditioner, electric vehicle, the traditional AC distribution network is no longer efficient.
Qi Xu   +5 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Studies of in-service and laboratory failures of metal-oxide distribution surge arresters

open access: yes, 2003
We describe the findings from tests and inspections of arresters withdrawn from service, the results of laboratory studies with multipulse lightning currents and high temporary over-voltages, and comparisons of in-service and laboratory failure modes. We
Darveniza, M., Saha, T. K., Wright, S.
core  

New design of high voltage surge arresters [PDF]

open access: yes, 2004
Zinc-oxide material is an important and widely used element in the high voltage gapless surge arresters. Equally important is the usually polymeric insulating material used for the surge arrester housing. This work aims to develop a new design of gapless
Darus, Ahmad
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Dc fault current calculation method in MMC-HVDC grid considering current-limiting devices

open access: yesThe Journal of Engineering, 2019
This paper proposes a DC fault current calculation method to reveal the fault current evolution mechanism of the modular multilevel converter (MMC)-based HVDC grid.
Jianzhong Xu   +3 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy