Results 81 to 90 of about 257,977 (308)

Damage‐Free Passivation of Ambipolar OECTs with Fluoropolymer Film for Enhanced Performance and Stability Toward Reliable Biosignal Processing

Advanced Science, EarlyView.
A damage‐free iCVD fluoropolymer passivation strategy is introduced for ambipolar vertical OECTs. Vapor‐phase infiltration and thermal annealing induce nanoscale phase separation in the OMIEC channel, enhancing overall device performance. A single‐channel bipolar event‐driven spiking encoder is also demonstrated for electrocardiogram signal encoding ...
Junyeong Yang, Bohyun Lee, Hanna Lee, Mingyu Kim, Changsoon Choi, Jung Ah Lim, Youson Kim, Sung Gap Im   +7 more
wiley   +1 more source

Arrhythmia

, 2022
In this article, I touched on one of the open topics in medicine, like arrhythmia. Many people require specialized cardiac care.
Madaminovich, Salimov Saidaminbek
core  

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

Biventricular / Left Ventricular Pacing in Hypertrophic Obstructive Cardiomyopathy: An Overview

Indian Pacing and Electrophysiology Journal, 2012
Hypertrophic cardiomyopathy (HCM) is an autosomal dominant inherited genetic disease characterized by compensatory pathological left ventricle (LV) hypertrophy due to sarcomere dysfunction.
Radu Vatasescu, MD, Reinder Evertz, MD, Lluis Mont, MD, PhD, Marta Sitges, MD, PhD, Josep Brugada, MD, PhD, Antonio Berruezo, MD, PhD   +5 more
doaj   +1 more source

Antigen‐Detected NMR for Minimal Epitope Engineering and Structure‐Guided Selection of a NaV1.7‐Selective Nanobody

Advanced Science, EarlyView.
A minimal extracellular epitope from voltage‐gated sodium channel NaV1.7 was engineered into an isotope‐labelled antigen for antigen‐detected nuclear magnetic resonance (NMR). Together with AlphaFold2 (AF2), this enabled structure‐guided selection of R4C8, a human NaV1.7‐selective nanobody that labels fixed NaV1.7‐expressing cells and produces staining
Junyu Liu, Wanlin Chen, Ben Cristofori‐Armstrong, Theo Crawford, Kai‐En Chen, Peng Xie, Rainbow Wing Bo Chan, Yifei Zhu, Mimi Golder, Anneka Pereira Schmidt, Jennifer D. Naughton, Nicholas D. Condon, Åsa Andersson, Farhad Dehkhoda, Kirsten L. McMahon, Tabea Klasfauseweh, Ashvriya Thapa, Hue Tran, Poanna Tran, Sina Jami, Lotten Ragnarsson, Sebastian G. B. Furness, Jennifer R. Deuis, Brett M. Collins, Wai‐Hong Tham, Indira Prasadam, Irina Vetter, Mehdi Mobli   +27 more
wiley   +1 more source

An Intraoperative Fluoroscopic Predictor of Successful Micra Implantation on the Right Ventricular Mid‐Septum

Journal of Arrhythmia
Background The Micra transcatheter pacing system has been adopted globally. However, the procedural parameters for safe Micra implantation on the ventricular wall, particularly in the mid‐septum, remain unknown.
Misun Pak, Ken Kakita, Takashi Yamasaki, Tetsuhisa Hattori   +3 more
doaj   +1 more source

Organic Electrochemical Transistors for Neuromorphic Bioelectronics: Materials and Manufacturing Technologies

Advanced Science, EarlyView.
Organic electrochemical transistors bridge biological ionic signaling and neuromorphic computation through volumetric electrochemical gating. This review connects Organic mixed ionic–electronic conductor materials, device architectures, and manufacturing technologies to show how geometry, ion transport, and fabrication strategies program plasticity ...
Hyunjin Lee, Jihyang Park, Xinyi Wang, Yueqi Deng, Jiashu Ren, Tao Zhou   +5 more
wiley   +1 more source

Nearly fatal ventricular arrhythmia following pacemaker implantation in a young female with complete heart block

Journal of Arrhythmia, 2019
This case concerns a 24‐year‐old female who developed malignant ventricular tachyarrhythmia a few weeks after pacemaker implantation for complete heart block.
Hussam Ali, Pierpaolo Lupo, Sara Foresti, Guido De Ambroggi, Riccardo Mantovani, Carmine De Lucia, Ilaria Passarelli, Luigi De Ambroggi, Riccardo Cappato   +8 more
doaj   +1 more source

Galectin-3 Regulates Atrial Fibrillation Remodeling and Predicts Catheter Ablation Outcomes

JACC: Basic to Translational Science, 2016
Atrial fibrillation (AF) usually starts as paroxysmal but can evolve relentlessly to the persistent and permanent forms. However, the mechanisms governing such a transition are unknown.
Yoshio Takemoto, MD, PhD, Rafael J. Ramirez, PhD, Miki Yokokawa, MD, Kuljeet Kaur, PhD, Daniela Ponce-Balbuena, PhD, Mohamad C. Sinno, MD, B. Cicero Willis, MD, Hamid Ghanbari, MD, Steven R. Ennis, PhD, Guadalupe Guerrero-Serna, PhD, Bettina C. Henzi, MD, Rakesh Latchamsetty, MD, Roberto Ramos-Mondragon, PhD, Hassan Musa, PhD, Raphael P. Martins, MD, Sandeep V. Pandit, PhD, Sami F. Noujaim, PhD, Thomas Crawford, MD, Krit Jongnarangsin, MD, Frank Pelosi, MD, Frank Bogun, MD, Aman Chugh, MD, Omer Berenfeld, PhD, Fred Morady, MD, Hakan Oral, MD, José Jalife, MD   +25 more
doaj   +1 more source

Periostin‐CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy

Advanced Science, EarlyView.
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Tiantian Wu, Ruotong Li, Xiaoyue Zhang, Dandan Chen, Jianmeng Yang, Mengmeng Li, Yuhan Yin, Ya Wang, Yuqiu Tian, Haoling Yan, Dan Cui, Jiangping Song, Gaoliang Ouyang   +12 more
wiley   +1 more source