Results 41 to 50 of about 194,887 (218)

Use of hiPSC-Derived Cardiomyocytes to Rule Out Proarrhythmic Effects of Drugs: The Case of Hydroxychloroquine in COVID-19

Frontiers in Physiology, 2022
In the early phases of the COVID-19 pandemic, drug repurposing was widely used to identify compounds that could improve the prognosis of symptomatic patients infected by SARS-CoV-2.
Luca Sala, Vladislav Leonov, Vladislav Leonov, Manuela Mura, Federica Giannetti, Aleksandr Khudiakov, Alessandra Moretti, Alessandra Moretti, Lia Crotti, Lia Crotti, Lia Crotti, Massimiliano Gnecchi, Massimiliano Gnecchi, Peter J. Schwartz   +13 more
doaj   +1 more source

The Pharmacological Management of Cardiac Arrhythmias [PDF]

, 2018
This thesis discuss the pharmacological management of cardiac arrhythmias which have developed diversely over the last century. There are mostly channel blockers affecting the sodium and potassium channels to prevent rhythm generation or delay its ...
Talab, Fahad
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Do K_ATP channels open as a prominent and early feature during ischaemia in the Langendorff-perfused rat heart? [PDF]

, 2000
The objective was to investigate whether myocardial adenosine triphosphate-sensitive K⁺ (K_ATP) channels open during the first 10 min of regional ischaemia in Langendorff-perfused rat hearts.
Northover, B.J., MacKenzie, I., Workman, A.J.   +2 more
core   +1 more source

Epidemiology of inherited arrhythmias [PDF]

, 2020
The primary electrical disorders are a group of inherited cardiac ventricular arrhythmias that are a major cause of sudden cardiac death in young individuals.
Connie R. Bezzina, Joost A. Offerhaus, Offerhaus, Joost A., Arthur A. M. Wilde, Wilde, Arthur A. M., Bezzina, Connie R.   +5 more
core   +1 more source

Arrhythmias May Hide a Genetic Cardiomyopathy in Left Ventricular Hypertrabeculation in Children: A Single-Center Experience

Children
Background. Left ventricular hypertrabeculation (LVHT) is a myocardial disorder with different clinical manifestations, from total absence of symptoms to heart failure, arrhythmias, sudden cardiac death (SCD), and thromboembolic events. It is challenging
Irma Battipaglia, Nicoletta Cantarutti, Marianna Cicenia, Rachele Adorisio, Virginia Battista, Anwar Baban, Massimo Stefano Silvetti, Fabrizio Drago   +7 more
doaj   +1 more source

Effects of age on the prevalence of cardiac dysrhythmias in ponies [PDF]

, 2010
This study describes the prevalence of cardiac dysrhythmias occurring over a single 24 h period in ponies and compares the heart rate and frequency of dysrhythmias in two groups of ponies of different ages Electrocardiograms were recorded using a Holter ...
Pirie, Scott; id_orcid, Rezakhani, A., Blissitt, Karen   +2 more
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Protecting the ischemic heart : pharmacological protection against myocardial ischemia in rats in vivo and in vitro [PDF]

, 2004
Today in Switzerland approximately 40% of all deaths are due to cardiovascular diseases. More than half of these are due to ischemic heart disease. Among the fatal consequences of ischemic heart disease are life-threatening arrhythmias and myocardial ...
Butz, Silvia
core   +1 more source

Remodeling of Ion Channel Trafficking and Cardiac Arrhythmias

Cells, 2021
Both inherited and acquired cardiac arrhythmias are often associated with the abnormal functional expression of ion channels at the cellular level. The complex machinery that continuously traffics, anchors, organizes, and recycles ion channels at the ...
Camille E. Blandin, Basile J. Gravez, Stéphane N. Hatem, Elise Balse   +3 more
doaj   +1 more source

ALCOHOL AND HEART RHYTHM DISORDERS

Рациональная фармакотерапия в кардиологии, 2015
Alcohol abuse and particularly extension of alcohol consumption in alcohol diseas increases the risk of cardiac arrhythmias development and aggravates existing arrhythmias.
A. O. Yusupova, A. S. Lishuta
doaj   +3 more sources

Estudio de los mecanismos de las arritmias cardiacas mediante modelado y procesado robusto digital de señal [PDF]

, 2008
Las arritmias cardiacas son alteraciones del funcionamiento eléctrico normal del corazón. Algunas, las arritmias patológicas, son potencialmente malignas y constituyen una de las principales causas de mortalidad en el mundo occidental.
Alonso Atienza, Felipe
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