Results 141 to 150 of about 489,421 (410)
Endothelin and the ischaemic heart [PDF]
Soon after its identification as a powerful vasoconstrictor peptide, endothelin (ET-1) was implicated as a detrimental agent involved in determining the outcome of myocardial ischaemia and reperfusion.
Kane, K.A., McCabe, C., Wainwright, C.L.
core +1 more source
Diabetes and Arrhythmias: Pathophysiology, Mechanisms and Therapeutic Outcomes
The prevalence of diabetes is rapidly increasing and closely associated with cardiovascular morbidity and mortality. While the major cardiovascular complication associated with diabetes is coronary artery disease, it is becoming increasingly apparent ...
Laurel A. Grisanti
semanticscholar +1 more source
Doxorubicin‐induced cardiomyopathy involves mitochondrial energy metabolism dysfunction, exacerbated by cardiomyocyte‐specific Slc25a49 deficiency via oxidative phosphorylation (OXPHOS) suppression and glycolysis activation. The Slc25a49–glucose‐6‐phosphate (G6P)–activator protein‐1 (AP‐1) axis drives myocardial injury by upregulating Sln, disrupting ...
Sitong Wan+16 more
wiley +1 more source
Method to Annotate Arrhythmias by Deep Network [PDF]
This study targets to automatically annotate on arrhythmia by deep network. The investigated types include sinus rhythm, asystole (Asys), supraventricular tachycardia (Tachy), ventricular flutter or fibrillation (VF/VFL), ventricular tachycardia (VT).
arxiv +1 more source
A study of early afterdepolarizations in a model for human ventricular tissue [PDF]
Sudden cardiac death is often caused by cardiac arrhythmias. Recently, special attention has been given to a certain arrhythmogenic condition, the long-QT syndrome, which occurs as a result of genetic mutations or drug toxicity. The underlying mechanisms
Kazbanov, Ivan+5 more
core +3 more sources
This study presents an ECRAM‐based physical reservoir computing system for real‐time electrocardiogram arrhythmia detection. By optimizing electrolyte ionic conductivity and channel ionic diffusivity, it achieves including non‐linear dynamics, millisecond‐scale tunable retention, low‐power operation, and minimal variation.
Kyumin Lee+3 more
wiley +1 more source
Medium‐chain Acyl‐COA dehydrogenase deficiency: Pathogenesis, diagnosis, and treatment
MCADD is a commonly inherited metabolic disease with serious implications for health outcomes, particularly in children, that may be successfully managed with proper intervention. In this review, we discuss the genetics, pathogenesis, clinical presentation, diagnosis, and treatments for Medium‐Chain Acyl‐CoA Dehydrogenase Deficiency (MCADD ...
Emily Mason+2 more
wiley +1 more source
Retrospective study of the correlation of serum potassium concentrations and the findings of heart auscultation in calves with neonatal diarrhea [PDF]
A retrospective study was conducted of clinical records of calves with neonatal diarrhea up to the age of 14 days concerning certain aspects of blood potassium concentration and heart rate and rhythm.
Acres, Stephen D., Klee, Wolfgang
core +1 more source
Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice
Diabetes mellitus (DM) encompasses a multitude of secondary disorders, including heart disease. One of the most frequent and potentially life threatening disorders of DM-induced heart disease is ventricular tachycardia (VT).
G. Monnerat+19 more
semanticscholar +1 more source