Results 111 to 120 of about 105,745 (208)

Electrocardiographic criteria in founder mutations related to Arrhythmogenic cardiomyopathy

, 2018
Founder mutations are rare causes in arrhythmogenic cardiomyopathy including TMEM43 und phospholamban mutations. The incidence is approximately 1%. P.S358L TMEM43 mutations cause aggressive, in most cases biventricular arrhythmogenic cardiomyopathy [1 ...
Peters Stefan, Stefan Peters*
core   +1 more source

Genotype-phenotype correlations in patients with pathogenic/likely pathogenic titin variants from the Swiss Arrhythmogenic Cardiomyopathy Registry

Open Heart
Background Truncating variants in the titin gene (TTNtv) are associated with cardiomyopathy, mainly dilated cardiomyopathy (DCM). The clinical presentation and outcomes of arrhythmogenic phenotypes in these patients are scarcely studied.Methods and ...
Andreas J Flammer, Lorraine Sazgary, Robert Manka, Annina Salome Vischer, Ardan M Saguner, Frank Ruschitzka, Marina Rieder, Siv Fokstuen, Firat Duru, Umberto Maccio, Argelia Medeiros-Domingo, Corinna Brunckhorst, Felix Tanner, Verena Charlotte Wilzeck, Nina Alissa Schätti, Matthias P. Nägele, Fran Mikulicic, Christian Grebmer, Katja E Odening, Nicole R Bonetti   +19 more
doaj   +1 more source

Catheter Ablation Versus Medical Therapy in Atrial Fibrillation With Heart Failure With Reduced or Mildly Reduced Ejection Fraction: A GRADE‐Assessed Systematic Review and Meta‐Analysis

Journal of Arrhythmia, Volume 42, Issue 5, October 2026.
In patients with atrial fibrillation and HFmrEF/HFrEF, catheter ablation was associated with lower mortality and improved cardiac function compared with conventional medical therapy, while cardiovascular hospitalization was not significantly reduced. The overall certainty of evidence ranged from moderate to high.
Aleena Amir Malik, Nasir Saeed, Goodluck Oparaugo, Muhammad Waqar Shahid, Waqas Kareem, Fatima Yousaf, Zain Ul Abedeen, Fatima Sajjad, Kashif Yousaf, Fizza Kazmi, Rubab Zahra, Ishfaq Ali, Sahil Kumar, Tanzeela Gul, Zartasha Rahim, Abdul Basit, Manal Sharif, Anum Noor, Habib ur Rehman, Imdad Ullah Shah, Abdullah Afridi   +20 more
wiley   +1 more source

High‐Density Spectral Analysis for Bi‐Atrial Arrhythmogenic Substrate During Non‐Paroxysmal Atrial Fibrillation

Journal of Arrhythmia, Volume 42, Issue 5, October 2026.
Analyzing 48 153 CARTOFINDER mapping points revealed that both FoA and RoA sites demonstrated elevated DF deviation (DFD) and RI compared to non‐sites. While both metrics increased progressively with FoA repetitions, high‐repetition RoA sites paradoxically displayed lower values.
Nobunari Tomura, Keitaro Senoo, Taku Ohkawa, Yusuke Kakei, Kohei Kawai, Masahiro Makino, Jun Munakata, Tomonori Miki, Yukinori Kato, Kento Fukui, Hiroki Kitajima, Suguru Nishiuchi, Ken Kakita, Daisuke Sato, Hirokazu Shiraishi, Satoaki Matoba   +15 more
wiley   +1 more source

Arrhythmogenic Left Ventricular Cardiomyopathy: From Diagnosis to Risk Management

Purpose of Review: Left ventricular arrhythmogenic cardiomyopathy (ALVC) is a rare and poorly characterized cardiomyopathy that has recently been reclassified in the group of non-dilated left ventricular cardiomyopathies.
Roma, Anna Selvaggia, Francesco S. Loffredo, Antonia Ascrizzi, Molinari, Riccardo, Mauriello, Alfredo, Antonello D’Andrea, Vincenzo Russo, Alfredo Mauriello, Russo, Vincenzo, Ascrizzi, Antonia, Riccardo Molinari, Loffredo, Francesco S., D'Andrea, Antonello, Anna Selvaggia Roma   +13 more
core   +1 more source

The role of macrophage migration inhibitory factor (MIF) in the pathogenesis and progression of cardiovascular disease

British Journal of Pharmacology, Volume 183, Issue 19, Page 5732-5751, October 2026.
Abstract Cardiovascular disease (CVD) remains the leading global cause of death, driven by complex mechanisms, in which chronic inflammation plays a central role. Inflammatory pathways contribute to all stages of CVD, from endothelial dysfunction and plaque formation to erosion, rupture and myocardial injury.
Shreya Mahabhashyam, James Harris, Jürgen Bernhagen, Antony Vinh, Katrina M. Mirabito Colafella   +4 more
wiley   +1 more source

Pathologic evidence of arrhythmogenic cardiomyopathy and myocarditis in two siblings

, 1998
This report describes the case of two siblings who underwent heart transplantation with a clinical diagnosis of mildly dilated cardiomyopathy. Pathological examination of the hearts revealed arrhythmogenic (right ventricular) cardiomyopathy. adipose type,
Carla Giordano, DE BIASE, Luciano, Anna Laurenti, GIORDANO, Carla, Giulia d’Amati, GALLO, Pietro, D'AMATI, Giulia, Fabio Fiore, Luciano De Biase, Pietro Gallo   +9 more
core   +1 more source

Natural Course of Electrocardiographic Features in Arrhythmogenic Right Ventricular Cardiomyopathy and Their Relation to Ventricular Arrhythmic Events

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Electrocardiographic abnormalities are common in arrhythmogenic right ventricular cardiomyopathy and are included in the 2010 Task Force Criteria. Their time course, however, remains uncertain.
Anneli Svensson, Henrik Kjaerulf Jensen, Machteld J. Boonstra, Marianne Tétreault‐Langlois, Pia Dahlberg, Henning Bundgaard, Alex Hørby Christensen, Rebecca T. Rylance, Jesper H. Svendsen, Julia Cadrin‐Tourigny, Anneline S. J. M. te Riele, Pyotr G. Platonov   +11 more
doaj   +1 more source

Racial and Ethnic Disparities in Acute Myocarditis Outcomes in the United States

Clinical Cardiology, Volume 49, Issue 9, September 2026.
In a nationally representative analysis of 105 235 U.S. hospitalizations for acute myocarditis, racial and ethnic minority groups had higher adjusted in‐hospital mortality than White patients. Asian/Pacific Islander patients had the greatest mortality and hemodynamic risk, while Black and Hispanic patients showed distinct complication patterns ...
Maria F. Osorio, Paola Lecompte‐Osorio, Sebastian Vasquez‐Ariza, Michael Dangl, Louis Vincent, Johanna Contreras, Rosario Colombo   +6 more
wiley   +1 more source

From Common Pathway to Divergent Diseases: Metabolic Aspects of Inborn Errors of CoA Biosynthesis

Journal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.
ABSTRACT Coenzyme A (CoA) biosynthesis is a conserved, dynamically regulated pathway essential for mitochondrial energy production, fatty acid oxidation, lipid biosynthesis and protein acylation. Biallelic variants in PANK2, PPCS, PPCDC, and COASY cause rare inborn errors of CoA biosynthesis, associated with markedly different clinical phenotypes ...
Ivano Di Meo, Yair Anikster, Valeria Tiranti, Arcangela Iuso   +3 more
wiley   +1 more source