Results 91 to 100 of about 105,745 (208)

Right ventricular assessment of the adolescent footballer’s heart

Echo Research and Practice
Introduction Athletic training can result in electrical and structural changes of the right ventricle that may mimic phenotypical features of arrhythmogenic right ventricular cardiomyopathy (ARVC), such as T-wave inversion and right heart dilatation.
D. X. Augustine, J. Willis, S. Sivalokanathan, C. Wild, A. Sharma, A. Zaidi, K. Pearce, G. Stuart, M. Papadakis, S. Sharma, A. Malhotra   +10 more
doaj   +1 more source

The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity

The Journal of Physiology, EarlyView.
Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas, Debbie J. Otto, Daniel Stratton, Katja Rietdorf, Daniel M. Johnson, Calum J. McMullen   +5 more
wiley   +1 more source

Distribution of biventricular disease in arrhythmogenic cardiomyopathy: an autopsy study

, 2012
Arrhythmogenic cardiomyopathy is a rare cardiomyopathy characterized by fibrofatty replacement primarily of the right ventricular myocardium. It is a major cause of sudden death in the young and in athletes.
Li, Ling, Ling Li, Nathaniel Cresswell, Allen Burke, Marcello Franco, Ziqin Zhao, Franco, Marcello [UNIFESP], Fabio Tavora, David Fowler, Fowler, David, Tavora, Fabio [UNIFESP], Oliveira, Joao Bosco, Burke, Allen, Zhao, Ziqin, Cresswell, Nathaniel, Mingchang Zhang, Zhang, Mingchang, Joao Bosco Oliveira   +17 more
core   +1 more source

LV‐predominant arrhythmogenic cardiomyopathy related to pathogenic DSP‐variant

Clinical Case Reports
Key Clinical Message In contrast to previously thought, arrhythmogenic cardiomyopathy can occur exclusively in the left ventricle in association with autosomal dominant mutation, even without any skin manifestations.
Soban Ahmad, Husam El Sharu, Robin Fernandes, Mark Kolasa, Constantin Bogdan Marcu   +4 more
doaj   +1 more source

Catheter Ablation of Ventricular Tachycardia in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia: A Sequential Approach

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background It has been suggested that endocardial and epicardial ablation of ventricular tachycardia (VT) improves outcome in arrhythmogenic right ventricular cardiomyopathy/dysplasia.
Shibu Mathew, Ardan M. Saguner, Niklas Schenker, Lukas Kaiser, Pengpai Zhang, Yoshiga Yashuiro, Christine Lemes, Thomas Fink, Tilman Maurer, Francesco Santoro, Peter Wohlmuth, Bruno Reißmann, Christian H. Heeger, Roland Tilz, Erik Wissner, Andreas Rillig, Andreas Metzner, Karl‐Heinz Kuck, Feifan Ouyang   +18 more
doaj   +1 more source

Cellular mechanisms of radiation‐induced myocyte dysfunction: effects on calcium handling, ion channel regulation and mitochondrial energetics

The Journal of Physiology, EarlyView.
Abstract figure legend Dose‐dependent effects of radiation on cardiac electrophysiology and arrhythmia susceptibility. At low radiation doses (left), increased reactive oxygen species (ROS) initiate an ROS–Ca2+ positive feedback loop involving calcium/calmodulin‐dependent protein kinase II (CaMKII) activation, enhanced L‐type Ca2+ current (ICaL ...
Hannah M. Zukowski, Colleen E. Clancy
wiley   +1 more source

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

The Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière, Thomas Boulin, Maëlle Jospin, Alexandre Janin, Gilles Millat, Philippe Chevalier, Olga Andrini   +6 more
wiley   +1 more source

Arrhythmogenic Right Ventricular Cardiomyopathy.

, 2012
Arrhythmogenic disorders of genetic origin include structural cardiomyopathies and inherited arrhythmic syndromes(1). Arrhythmogenic right ventricular cardiomyopathy (ARVC) is listed among the former, since it is characterized by structural and ...
BAUCE, BARBARA, THIENE, GAETANO, BASSO, CRISTINA, CORRADO, DOMENICO   +3 more
core   +1 more source

Arrhythmogenic ventricular cardiomyopathy and sudden cardiac death: Left or right? [PDF]

, 2017
Arrhythmogenic right ventricular cardiomyopathy is a leading cause of sudden cardiac death among athletes in Italy and the Mediterranean region. Although it often involves the right ventricle causing scarring, dilation, systolic impairment with aneurysm ...
AlJaroudi, Wael A., Abi-Saleh, Bernard S., Mansour, Bilal, Rachoin, Rachoin, Rachwan, Rayan Jo   +4 more
core   +1 more source

Intercalated disk structure, tissue heterogeneity and ion channel distribution modulate conduction and local calcium influx

The Journal of Physiology, EarlyView.
Abstract figure legend A, three‐dimensional representation of cardiac intercalated disk, reduced to a 100‐partition, computationally efficient network representation. B, ion dynamics within intercalated disk extracellular cleft space. C, rapid pacing leads to localized conduction block in tissue with regions of perturbed intercalated disk (ID ...
Nicolae Moise, Heather L. Struckman, James W. Smyth, Gregory S. Hoeker, Steven Poelzing, Rengasayee Veeraraghavan, Seth H. Weinberg   +6 more
wiley   +1 more source