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Pathobiology of Arrhythmogenic Cardiomyopathy
Cardiac Electrophysiology Clinics, 2011This article discusses recent advances in the pathology and pathogenesis of arrhythmogenic cardiomyopathy (AC) that have led to the current perspective of a genetically determined cardiomyopathy. AC was initially believed to be a developmental defect of the right ventricular (RV) myocardium, thus justifying the original designation of dysplasia.
BASSO, CRISTINA +5 more
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Pathophysiology of arrhythmogenic cardiomyopathy
Nature Reviews Cardiology, 2011Arrhythmogenic cardiomyopathy (AC) is a clinically and genetically heterogeneous disorder of heart muscle that is associated with ventricular arrhythmias and risk of sudden cardiac death, particularly in the young and athletes. Mutations in five genes that encode major components of the desmosomes, namely junction plakoglobin, desmoplakin, plakophilin ...
BASSO, CRISTINA +3 more
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The Pathobiology of Arrhythmogenic Cardiomyopathy
Annual Review of Pathology: Mechanisms of Disease, 2011This review highlights current knowledge about arrhythmogenic cardiomyopathy and considers clinical, pathological, genetic, biomechanical, and pathophysiological aspects of disease pathogenesis. Although relatively uncommon, arrhythmogenic cardiomyopathy is of particular interest as a model system for study.
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Arrhythmogenic Cardiomyopathy and Sports Activity
Journal of Cardiovascular Translational Research, 2020Arrhythmogenic right-ventricular cardiomyopathy (ARVC) is a genetically determined heart disease characterized by progressive myocyte death and substitution by fibrofatty tissue. Life-threatening ventricular arrhythmias may occur during the course of the disease and are distinctively triggered by sports activity: for this reason, ARVC is one of the ...
Zorzi, Alessandro +5 more
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[Early-onset arrhythmogenic cardiomyopathy].
Giornale italiano di cardiologia (2006), 2023Caso di cardiomiopatia aritmogena destra con esordio in eta ...
De Raffele, Martina, Passarini, Giulia
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Progress in Cardiovascular Diseases, 2019
Sudden cardiac death (SCD) is a devastating possible outcome of all cardiomyopathies. The risk of SCD is increased in patients with structural heart disease and continues to increase as ventricular dysfunction worsens. There is, however, a subset of cardiomyopathy, so-called "arrhythmogenic cardiomyopathy" (ACM), that carries an inherent propensity for
Zackary D, Goff, Hugh, Calkins
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Sudden cardiac death (SCD) is a devastating possible outcome of all cardiomyopathies. The risk of SCD is increased in patients with structural heart disease and continues to increase as ventricular dysfunction worsens. There is, however, a subset of cardiomyopathy, so-called "arrhythmogenic cardiomyopathy" (ACM), that carries an inherent propensity for
Zackary D, Goff, Hugh, Calkins
openaire +2 more sources