Cardiac digital twins: Modelling the arrhythmic substrate of chemotherapy
The Journal of Physiology, EarlyView.
Radomir Chabiniok, Vlad G. Zaha
wiley +1 more source
ABSTRACT Accurate assessment of right ventricular wall thickness, myocardial visualization, and chamber dimensions is crucial in veterinary cardiology but remains understudied in dogs. This prospective observational study evaluated 10 healthy beagle dogs to compare three echocardiographic approaches for assessing right ventricular parameters: sector ...
Yeonju Park +5 more
wiley +1 more source
Selective RyR2 inhibition reduces arrhythmia susceptibility in human cardiac slices
Abstract figure legend ent‐Vert selectively inhibits RyR2‐mediated sarcoplasmic reticulum (SR) Ca2+ leak and prevents triggered activity in human cardiac slices. A, in human ventricular slices exposed to β‐adrenergic stimulation with Iso and RyR2 sensitization with caffeine, RyR2 channels become hyperactive, leading to Ca2+ sarcoplasmic leak and ...
Micah K. Madrid +6 more
wiley +1 more source
Patient and Disease-Specific Induced Pluripotent Stem Cells for Discovery of Personalized Cardiovascular Drugs and Therapeutics. [PDF]
Human induced pluripotent stem cells (iPSCs) have emerged as an effective platform for regenerative therapy, disease modeling, and drug discovery.
Chandy, Mark +2 more
core
Background Electrocardiographic abnormalities are common in arrhythmogenic right ventricular cardiomyopathy and are included in the 2010 Task Force Criteria. Their time course, however, remains uncertain.
Anneli Svensson +11 more
doaj +1 more source
Arrhythmogenic Cardiomyopathy: Focus on Imaging
Arrhythmogenic cardiomyopathy (AC) is a broad term denoting subclinical or clinical heart muscle disease which presents predominantly with serious arrhythmias.
Madhu Shukla +3 more
doaj +1 more source
ATIPICIDADES EN UN CASO CON DISPLASIA ARRITMOGÉNICA DEL VENTRÍCULO DERECHO O ENFERMEDAD DE UHL / Report of an atypical case with arrhythmogenic right ventricular dysplasia or Uhl´s anomaly [PDF]
ResumenLa displasia arritmogénica del ventrículo derecho es una miocardiopatía caracterizada por arritmias ventriculares malignas y anomalías estructurales progresivas, que afectan primariamente al ventrículo derecho.
Ana M. Jerez Castro +4 more
core
Frequency estimation of disease-causing mutations in the Belgian population of some dog breeds, part 2 : retrievers and other breed types [PDF]
A Belgian population of ten breeds with a low to moderately low genetic diversity or which are relatively popular in Belgium, i.e. Bichon frise, Bloodhound, Bouvier des Flandres, Boxer, Cavalier King Charles spaniel, Irish setter, Papillon, Rottweiler ...
Beckers, Evy +3 more
core
Arrhythmogenic Cardiomyopathy and Biomarkers: A Promising Perspective? [PDF]
Barocelli F +13 more
europepmc +1 more source

