Results 51 to 60 of about 4,606 (191)

Long‐Term Outcomes of Catheter Ablation in Ventricular Tachycardia Electrical Storm: A Retrospective Cohort Study

Clinical Cardiology, Volume 48, Issue 11, November 2025.
Despite high acute success, catheter ablation for electrical storm is associated with substantial recurrence and mortality. This study emphasizes the complex substrate and high‐risk profile of this population, underscoring the need for careful long‐term management.
Cem Çöteli, Samuray Zekeriyayev, Can Sezer, Hikmet Yorgun, Kudret Aytemir   +4 more
wiley   +1 more source

New insights into applications of base editor in hereditary disorders

Interdisciplinary Medicine, Volume 3, Issue 6, November 2025.
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai, Linhui Zhang, Liqing Li, Yue Liu, Canbin Lv, Yan Shi, Jianyuan Zhao, Dingwei Ye, Yuanyuan Qu   +8 more
wiley   +1 more source

Atrial Fibroblasts‐Derived Extracellular Vesicles Exacerbate Atrial Arrhythmogenesis

Advanced Science, Volume 12, Issue 37, October 6, 2025.
Exosome miR‐224‐5p derived from angiotensin II‐treated atrial fibroblasts creates a substrate for AF by promoting atrial electrical remodeling. Increased exosome miR‐224‐5p enhances AF susceptibility by inhibiting CACNA1c expression and decreasing ICa current of atrial cardiomyocytes.
Yue Yuan, Xinbo Zhao, Xuejie Han, Yukai Cao, Xuexin Jin, Ling Shi, Xin Bi, Desheng Li, Yun Zhang, Wenbo Ma, Jiahui Song, Zhenwei Pan, Zhiren Zhang, Yue Li   +13 more
wiley   +1 more source

Genome Sequencing Uncovers Additional Findings in Phelan‐McDermid Syndrome

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 198, Issue 7, Page 126-134, October 2025.
ABSTRACT Phelan‐McDermid syndrome (PMS) is a genetic condition caused by deletions of chromosome 22q13.3 or pathogenic variants in the SHANK3 gene. Neurologic features typically include intellectual disability, autism spectrum disorder, hypotonia, and absent speech, though there is considerable variability even among individuals with the same molecular
Rachel Gore Moses, Morgan Similuk, Alexandra Hehn, Rylee Duncan, Margaret Pekar, Eliza Gordon‐Lipkin, Maria T. Acosta, Deena Zeltser, Nadjalisse Reynolds‐Lallement, Latha Soorya, Mustafa Sahin, Tess Levy, Alexander Kolevzon, Joseph D. Buxbaum, Elizabeth Berry‐Kravis, Craig M. Powell, Jonathan A. Bernstein, Mari Tokita, Bryce A. Seifert, Rajarshi Ghosh, Magdalena A. Walkiewicz, Audrey Thurm   +21 more
wiley   +1 more source

Arrhythmogenic Right Ventricular Dysplasia — a Variant of Primary Cardiomyopathy

Zdorovʹe Rebenka, 2013
This article provides an own observation of family form of arrhytmogenic right ventricular dysplasia in a girl, which had been followed-up for 12 years.
G.E. Sukhareva, V.I. Sadovoy
doaj   +1 more source

Comparing Two‐Dimensional Ellipsoid Model Variants in Estimating Three‐Dimensional Echocardiographic Right Ventricular Volume in Dogs

Journal of Veterinary Internal Medicine, Volume 39, Issue 5, September/October 2025.
ABSTRACT Background Determining right ventricular (RV) volume typically requires three‐dimensional imaging due to its complex shape. The ellipsoid model offers a two‐dimensional alternative, employing area‐ or linear‐based formulas with further variations depending on the echocardiographic views used for measurements.
Robert Ciardullo, Brittany E. Tagg, Elisabeth Nesta, Shana B. Mintz, Romain Pariaut, Weihow Hsue   +5 more
wiley   +1 more source

Right atrial remodelling and prognosis in patients with severe atrial functional tricuspid regurgitation

ESC Heart Failure, Volume 12, Issue 4, Page 2909-2920, August 2025.
Abstract Aims Atrial functional tricuspid regurgitation (AFTR) is increasingly recognized as a distinct cause of tricuspid regurgitation, yet data on outcomes and their determinants are limited. This study examines the prognostic role of right atrial (RA) remodelling in patients with severe AFTR.
Soongu Kwak, Dong‐Jae Han, Seung‐Pyo Lee, Ho Young Hwang, Hyung‐Kwan Kim, Yong‐Jin Kim, Kyung Hwan Kim, Jae Woong Choi, Jun‐Bean Park   +8 more
wiley   +1 more source

Role of Catheter Ablation in Arrhythmogenic Right Ventricular Dysplasia

Indian Pacing and Electrophysiology Journal, 2005
Arrhythmogenic right ventricular dysplasia/cardiomyopathy is a disorder characterized by frequent ventricular tachycardia originating from the right ventricle and fibro-fatty replacement of right ventricular myocardium. Though the disorder was originally
Guy Fontaine, Johnson Francis
doaj  

Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia: Mechanisms and Management

Research Reports in Clinical Cardiology, 2020
Ahmed AlTurki,1 Bader Alotaibi,1 Jacqueline Joza,1 Riccardo Proietti2 1Division of Cardiology, McGill University Health Center, Montreal, QC, Canada; 2Department of Cardiac, Thoracic, Vascular Sciences, and Public Health, University of Padua, Padua ...
AlTurki A, Alotaibi B, Joza J, Proietti R   +3 more
doaj  

Clinical Diagnosis, Imaging, and Genetics of Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia: JACC State-of-the-Art Review.

Journal of the American College of Cardiology, 2018
Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is an inherited cardiomyopathy that can lead to sudden cardiac death and heart failure. Our understanding of its pathophysiology and clinical expressivity is continuously evolving.
E. Gandjbakhch, alban redheuil, F. Pousset, P. Charron, R. Frank   +4 more
semanticscholar   +1 more source