Results 111 to 120 of about 1,471,016 (341)

Two Stages of Arrival Aircraft: Influencing Factors and Prediction of Integrated Arrival Time

open access: yesAerospace
To enhance the accuracy and real-time capability of estimated in-block time (EIBT) predictions at airports, this study proposes a two-stage integrated prediction method.
Xiaowei Tang   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Machine Learning Estimation of Fire Arrival Time from Level-2 Active Fires Satellite Data [PDF]

open access: gold, 2021
Angel Farguell   +5 more
openalex   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

A Bayesian Framework for Estimating Seismic Wave Arrival Time [PDF]

open access: yes, 2019
Because earthquakes have a large impact on human society, statistical methods for better studying earthquakes are required. One characteristic of earthquakes is the arrival time of seismic waves at a seismic signal sensor.
Zhong, Hua
core   +2 more sources

Generalizations of Kijowski's time-of-arrival distribution for interaction potentials

open access: yes, 2001
Several proposals for a time-of-arrival distribution of ensembles of independent quantum particles subject to an external interaction potential are compared making use of the ``crossing state'' concept.
A. D. Baute   +30 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

THE TOHOKU TSUNAMI OF 11 MARCH 2011 AS RECORDED ON THE RUSSIAN FAR EAST [PDF]

open access: yesScience of Tsunami Hazards, 2012
The source region of the catastrophic Tohoku tsunami of 11 March 2011 was near the Russian Far East, thus a warning was issued for threatened coasts of the Kuril Islands and Kamchatka.
G. V. Shevchenko, T. N. Ivelskaya
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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