Results 131 to 140 of about 339,172 (313)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Valuation of uncertainty in travel time and arrival time - some findings from a choice experiment [PDF]
We are developing a dynamic modeling framework in which we can evaluate the effects of different road pricing measures on individual choice behavior as well as on a network level.
Michiel Bliemer, Dirk Van Amelsfort
core
Reliable Denoising Strategy to Enhance the Accuracy of Arrival Time Picking of Noisy Microseismic Recordings. [PDF]
Sensors (Basel), 2023 Zhang X, Li H, Rong W.
europepmc +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
An appraisal of QR code use to deliver bus arrival time information at bus stops in Southampton
, 2011 The provision of at-stop bus arrival time information has numerous potential benefits to bus users. With real-time passenger information well established in the UK the challenge is relaying accurate bus arrival times to passengers in a cost effective ...
Gammer, Nick
core
Enhancing vessel arrival time prediction: A fusion-based deep learning approach
The logistic community of shippers has struggled to predict the precise arrival time of the seagoing vessels with reliable certainty. While deep-learning approaches are promising, the existing methods fail to provide desirable results due to a shallow ...
Amrit, C.; id_orcid, Abdi, A., Amrit, C.
core +1 more source
Assessing the efficacy of health countermeasures on arrival time of infectious diseases. [PDF]
Infect Dis Model, 2023 Asai Y.
europepmc +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Staffing service centers under arrival-rate uncertainty
, 2012 textWe consider the problem of staffing large-scale service centers with multiple customer classes and agent types operating under quality-of-service (QoS) constraints.
Zan, Jing, 1983-
core
A Comprehensive Survey on Short-Distance Localization of UAVs
DronesThe localization of Unmanned Aerial Vehicles (UAVs) is a critical area of research, particularly in applications requiring high accuracy and reliability in Global Positioning System (GPS)-denied environments.
Luka Kramarić +3 more
doaj +1 more source