Results 131 to 140 of about 67,640 (303)
Impact of Daily Maximum Temperature on Emergency Department Arrivals and Acuity Levels
Western Journal of Emergency MedicineIntroduction: Heatwaves are becoming more frequent and severe globally. Heat is associated with increases in emergency department (ED) volumes and higher morbidity for a range of chronic conditions.
Catharina Giudice +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
The M/M/c queue with mass exodus and mass arrivals when empty [PDF]
, 2015 Lina Zhang, Junping Li
openalex +1 more source
Behavioural Study of Market Arrivals and Prices of Tomato in Major Markets of Tamil Nadu - A Time Series Analysis [PDF]
, 2020 C. Tamilselvi +3 more
openalex +1 more source
The arrival of STEM in the science and mathematics curriculum increases the epistemic demands on teachers [PDF]
, 2022 Simon N. Leonard
openalex +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Forecasting Intraday Time Series with Multiple Seasonal Cycles Using Parsimonious Seasonal Exponential Smoothing [PDF]
This paper concerns the forecasting of seasonal intraday time series. An extension of Holt-Winters exponential smoothing has been proposed that smoothes an intraday cycle and an intraweek cycle.
Ralph D. Snyder, James W. Taylor
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
, 2010 Mean proportions of arrivals to the colony between 0400 and 0600 hours (sunrise hours) for each month of the study period (August 2007-March 2008). The statistically significant differences between numbers of arrivals and departures are indicated in the ...
Bonadonna, Francesco +11 more
core +1 more source