Results 171 to 180 of about 67,640 (303)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Modelling International Tourist Arrivals and Volatility: An Application to Taiwan [PDF]

International tourism is a major source of export receipts for many countries worldwide. Although it is not yet one of the most important industries in Taiwan (or the Republic of China), an island in East Asia off the coast of mainland China (or the ...
Michael McAleer, Dan Slottje, Chia-Lin Chang   +2 more
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Research of Forecasting on Tourist Arrivals to Malaysia

, 2019
Nur Faezah, Nor Mariyah, Abdul Ghafar, Mohd Zikri Mohd Zaki, Awang Chek, Isma Liana Ismail, Isma Liana Ismail, N Salem, S Carvao, I Jala, R Chen, C Liang, W Hong, D Gu, M Shitan, C Lim, M Mcaleer, J Kim, L Turner, S Safee, S Ahmad   +20 more
openalex   +1 more source

Impact of Negative Arrivals and Multiple Working Vacation on Dual Supplier Inventory Model with Finite Lifetimes

, 2021
M. L. Soujanya, P. Vijaya Laxmi, E.M.T. Sirisha   +2 more
openalex   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Effectiveness Analysis of Arrival-Departure Service in Sultan Hasanuddin International Airport Mandai South Sulawesi

Ramlawati Ramlawati, Rahmiati Rahmiati, Hasnawati Hasnawati, Andi Nurfadilah Yusra, Andi Nila Ratna Sari   +4 more
openalex   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Production Line Outsourcing Decisions at Arrival Time

Syed, Danish Abbas, Nasirimajd, Amirshayan, Quadrini, Walter   +2 more
openalex   +1 more source

Gamma‐Ray Burst Arrival Time Localizations: Simultaneous Observations byMars Observer,Compton Gamma Ray Observatory, andUlysses [PDF]

, 1997
J. G. Laros, W. V. Boynton, K. Hurley, C. Kouveliotou, M. L. McCollough, G. J. Fishman, C. Meegan, D. M. Palmer, T. L. Cline, R. Starr, J. I. Trombka, M. Boër, M. Niel, A. E. Metzger   +13 more
openalex   +1 more source