Results 81 to 90 of about 576,496 (275)

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons, Todd Levine, Charles H. Adler, Bailey Bellaire, Ningshan Wang, Pinky Agarwal, Georgina M. Aldridge, Alexandru Barboi, Daniel Claassen, Virgilio G. H. Evidente, Douglas Galasko, Alejandra Gonzalez‐Duarte, Ramon Gil, Mark Gudesblatt, Stuart H. Isaacson, Horacio Kaufmann, Pravin Khemani, Rajeev Kumar, Guillaume Lamotte, Andy J. Liu, Nikolaus R. McFarland, Mitchell G. Miglis, Adam Reynolds, Gregory A. Sahagian, Marie‐Helene Saint‐Hilaire, Julie B. Schwartzbard, Wolfgang Singer, Michael J. Soileau, Steven Vernino, Patricio Millar Vernetti, Oleg Yerstein, Roy Freeman   +31 more
wiley   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Two adaptive rejection sampling schemes for probability density functions log-convex tails [PDF]

, 2011
Monte Carlo methods are often necessary for the implementation of optimal Bayesian estimators. A fundamental technique that can be used to generate samples from virtually any target probability distribution is the so-called rejection sampling method ...
Martino, Luca, Míguez, Joaquín
core   +2 more sources

Statistical study of free magnetic energy and flare productivity of solar active regions

, 2014
Photospheric vector magnetograms from Helioseismic and Magnetic Imager on board the Solar Dynamic Observatory are utilized as the boundary conditions to extrapolate both non-linear force-free and potential magnetic fields in solar corona.
Jing, J., Su, J. T., Wang, H. M., Wang, S., Wiegelmann, T.   +4 more
core   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

The continuum intensity as a function of magnetic field I. Active region and quiet Sun magnetic elements

, 2011
Small-scale magnetic fields are major contributors to the solar irradiance variations. Hence, the continuum intensity contrast of magnetic elements in the quiet Sun (QS) network and in active region (AR) plage is an essential quantity that needs to be ...
Barthol, Berger, Berger, Berger, Berger, Borrero, Brooks, Danilovic, De Pontieu, Deinzer, Domingo, Frazier, Frazier, Hirzberger, Howard, Ichimoto, Ishikawa, Ishikawa, J. M. Borrero, Keller, Khomenko, Knölker, Knölker, Kobel, Komm, Kosugi, Krivova, Krivova, Krivova, Lagg, Lawrence, Lin, Lites, Lites, Lites, Lites, Morinaga, Muller, Narayan, Neckel, Orozco Suárez, P. Kobel, Rabin, Rabin, Rempel, Riethmüller, S. K. Solanki, Schuessler, Sheeley, Solanki, Solanki, Solanki, Solanki, Solanki, Spruit, Spruit, Spruit, Steiner, Stenflo, Stenflo, Stenflo, Suematsu, Title, Title, Title, Topka, Topka, Tsuneta, Uitenbroek, Viticchié, Vögler, Vögler, Walton, Zakharov, Zayer, Zhao   +75 more
core   +1 more source

TBK1‐Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We report a 58‐year‐old woman with a novel splice‐site variant in the TANK‐binding kinase 1 (TBK1:c.993–2A>C p.Ala332TyrfsTer39) who sequentially developed primary lateral sclerosis (PLS) followed by right temporal variant frontotemporal dementia (rtvFTD). Neuroimaging demonstrated right anterior temporal atrophy before cognitive symptoms, and
Tomoyasu Matsubara, Naoki Kihara, Satoko Miyatake, Koji Fujita, Konoka Tachibana, Ryosuke Miyamoto, Hiroki Yamazaki, Yusuke Osaki, Nazere Keyoumu, Yuki Kuwano, Nobutoshi Morimoto, Suzuran Saito, Eriko Koshimizu, Yoichi Otomi, Kenji Ishibashi, Masafumi Harada, Naomichi Matsumoto, Hiroyuki Morino, Yuishin Izumi   +18 more
wiley   +1 more source

Ars Electronica Festival 2024 - Festival für Kunst, Technologie und Gesellschaft

Medienimpulse
Aus erster Hand erfahren, wie neue Technologien unser Leben verändern. Selbst erleben, wie Machine Learning, VR, Robotik oder Biotech zu einem sozial und ökologisch nachhaltigen Fortschritt beitragen können.
Katharina Kaiser-Müller
doaj  

Risks of long-term use of nitrofurantoin for urinary tract prophylaxis in the older patient

Urological Science, 2016
Purpose: To review the current literature on reported pulmonary, liver, and nerve adverse reactions (ARs) of long-term Nitrofurantoin (NF) suppression in older patients treated for urinary tract infections (UTIs).
Lauren L. Rego, Craig S. Glazer, Philippe E. Zimmern   +2 more
doaj   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source