Results 191 to 200 of about 103,218 (267)

Examining the role of freebase nicotine in the harm reduction potential of oral nicotine pouches versus moist snuff: A randomized crossover trial

Addiction, EarlyView.
Abstract Background and aims Oral nicotine pouches (ONPs) contain varying proportions of freebase nicotine (FBN), with higher FBN expected to increase nicotine delivery across the oral mucosa. Because ONPs contain fewer toxicants than moist snuff and may serve as a reduced harm alternative for smokeless tobacco, we compared how the FBN in ONPs affects ...
Brittney Keller‐Hamilton, Hayley Curran, Leanne Atkinson, Sriya Suraapaneni, Alice Hinton, Kirsten Chrzan, Darren Mays, Ahmad El‐Hellani, Clark W. Wilson, Marielle C. Brinkman, Theodore L. Wagener   +10 more
wiley   +1 more source

Nrf2 activation by the monocarbonyl curcumin derivative GO-Y015 confers cellular protection against arsenite toxicity by reducing intracellular arsenic levels. [PDF]

Sci Rep
Islam MT, Taguchi H, Yamakoshi H, Yinuo W, Shibata H, Iwabuchi Y, Toyama T, Saito Y.   +7 more
europepmc   +1 more source

Nicotine pouches and clinical outcomes related to smoking cessation: A systematic review of randomized trials

Addiction, EarlyView.
Abstract Background and aims Tobacco‐free nicotine pouches (NPs) are oral nicotine products promoted by manufacturers and some researchers as tools that may reduce nicotine cravings and support smoking reduction or cessation. However, evidence regarding their actual clinical impact remains limited.
Javad Heshmati, Spencer Shahen, Emma Lynn Bates, Sarah Visintini, Evyanne Quirouette, Kerri‐Anne Mullen, Hassan Mir   +6 more
wiley   +1 more source

Human Milk as a Biomonitor of Toxic Metal Exposure: Sources, Transfer Mechanisms, and Implications for Infant Health-A Review. [PDF]

Nutrients
Katryńska D, Bzikowska-Jura A, Goc Z, Kogut Ł.   +3 more
europepmc   +1 more source

The Fiery Eyes of a Maenad: Origin Determination of Faceted Garnet Eye Inlays in a Roman Bronze Bust From Southern Tyrol

Archaeometry, EarlyView.
ABSTRACT In 1837, the Tyrolean State Museum Ferdinandeum in Innsbruck, Austria, purchased a Roman bronze statue of a maenad from the 2nd century ce with red garnets as facetted eye inlays found near Brixen, Southern Tyrol. These garnets were investigated using optical microscopy, a portable hand‐held and a stationary micro‐X‐ray fluorescence device, as
H. Albert Gilg, Simon Wagner, Anton Höck, Peter Tropper   +3 more
wiley   +1 more source

Antibody-Targeted Covalent Inhibitor Conjugate (Ab-TCI) Bridged by an Arsenic-Thiol Bond Enables "Double Insurance" Targeting of Cancer Cells and Kinase for Effective Cancer Treatment. [PDF]

ACS Med Chem Lett
Zhao X, Zhao Y, Fang Z, Wei N, Chen J, Wang Q, Yan X.   +6 more
europepmc   +1 more source

Early Bronze Age Copper Circulation in the Guadalentín and Segura Valleys (SE Spain)

Archaeometry, EarlyView.
ABSTRACT Identifying the sources of copper used in Early Bronze Age metalwork from south‐east Spain is key to resolving a long‐running debate concerning centralized control, or lack thereof, over El Argar society's economic organisation. This study provides the first substantial integrated programme of EDXRF and MC‐ICP‐MS analyses for copper‐base ...
Dirk Brandherm, Ignacio Montero‐Ruiz
wiley   +1 more source

Soil health to human health: impacts of soil contaminants on cardio-neurological health and clinical outcomes: a narrative review. [PDF]

Front Cardiovasc Med
Awosika A, Adeniyi MJ.
europepmc   +1 more source

Late Iron Age and Early Roman Brooches From the Lower Rhine Area: Provenance of the Metal Supply Traced Through Lead Isotopes

Archaeometry, EarlyView.
ABSTRACT Geochemical analysis of five brooch types from the Lower Rhine area dated to the last century bc and first century ad is used to constrain resource use, exchange and mobility. Lead isotope ratios demonstrate an Iberian provenance for copper in bronze Late Iron Age brooches.
A. A. T. Ruiter, B. J. H. van Os, J. B. V. Hermsen, G. R. Davies, S. W. Merkel   +4 more
wiley   +1 more source