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Correction: Arsenic trioxide and p97 inhibitor synergize against acute myeloid leukemia by targeting nascent polypeptides and activating the ZAKα-JNK pathway. [PDF]
Cancer Gene TherXie S +18 more
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Expert Opinion on Pharmacotherapy, 2008
The ancient drug, arsenic, has remarkable efficacy in the treatment of relapsed acute promyelocytic leukemia (APL) and this success has led to exploration of its use in other malignancies.To provide an overview of the mechanism of action of arsenic and summarize its development in the treatment of APL and other malignant disorders.A 20-year search of ...
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The ancient drug, arsenic, has remarkable efficacy in the treatment of relapsed acute promyelocytic leukemia (APL) and this success has led to exploration of its use in other malignancies.To provide an overview of the mechanism of action of arsenic and summarize its development in the treatment of APL and other malignant disorders.A 20-year search of ...
+7 more sources
Osteomyelitis due to arsenic trioxide use for tooth devitalization
International Endodontic Journal, 2007 Aim To present a case of osteomyelitis that was caused by the use of arsenic trioxide during root canal treatment in a mandibular left first molar. Summary Arsenic was once in common use to devitalize inflammed pulp tissue before root canal treatment ...
Vakur Olgaç +1 more
exaly +3 more sources
The Effects of Arsenic Trioxide on DNA Synthesis and Genotoxicity in Human Colon Cancer Cells
International Journal of Environmental Research and Public Health, 2010 Colon cancer is the third leading cause of cancer-related deaths worldwide. Recent studies in our laboratory have demonstrated that arsenic trioxide is cytotoxic in human colon cancer (HT-29), lung (A549) and breast (MCF-7) carcinoma cells.
Jacqueline J Stevens +2 more
exaly +2 more sources
The role of Akt on Arsenic trioxide suppression of 3T3-L1 preadipocyte differentiation
Cell Research, 2005 The present study investigates the molecular details of how arsenic trioxide inhibits preadipocyte differentiation and examines the role of Akt/PKB in regulation of differentiation and apoptosis.
Qiao Wu, Quan Chen, Wu Qiao
exaly +2 more sources