Results 181 to 190 of about 178,362 (241)

Targeting Metabolic Dependencies in Acute Myeloid Leukemia: A Dual Strategy using Arsenic Trioxide and Artesunate

open access: yes
Balasundaram N   +12 more
europepmc   +1 more source

Arsenic trioxide

Expert Opinion on Pharmacotherapy, 2008
The ancient drug, arsenic, has remarkable efficacy in the treatment of relapsed acute promyelocytic leukemia (APL) and this success has led to exploration of its use in other malignancies.To provide an overview of the mechanism of action of arsenic and summarize its development in the treatment of APL and other malignant disorders.A 20-year search of ...
  +9 more sources

Local delivery of arsenic trioxide nanoparticles for hepatocellular carcinoma treatment

open access: yesSignal Transduction and Targeted Therapy, 2019
Hepatocellular carcinoma (HCC) is a malignancy with a poor prognosis. Surgery combined with chemotherapy has been recommended as a curative regimen for HCC.
Jian Hu, Yi Dong, Li Ding
exaly   +2 more sources

Combination treatment with cyclosporin A and arsenic trioxide induce synergistic cell death via non-apoptotic pathway in uterine cervical cancer cells.

Chemico-Biological Interactions, 2022
Cyclosporin A is an immunosuppressive drug with anti-cancer effect. Arsenic trioxide (As2O3), a well-known cancer-inhibiting drug, induced cytotoxicity via apoptosis and autophagy.
Pei-Ju Wu   +5 more
semanticscholar   +1 more source

Delivery of Arsenic Trioxide by Multifunction Nanoparticles to Improve the Treatment of Hepatocellular Carcinoma.

ACS Applied Materials and Interfaces, 2020
BACKGROUND Arsenic trioxide (ATO) is effective in the treatment of hematological malignancies and solid tumors. However, its toxicity and side effects are severe, posing an obstacle in its clinical application.
Qirun Wu   +8 more
semanticscholar   +1 more source

Therapeutic strategy of arsenic trioxide in the fight against cancers and other diseases.

Metallomics, 2020
Arsenic trioxide (ATO) has been recognized as a drug for the treatment of various diseases in traditional medicine for more than two thousand years. Although ATO has recently shown excellent efficacy for the treatment of acute promyelocytic leukemia (APL)
Qian Qian Wang   +2 more
semanticscholar   +1 more source

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