Results 11 to 20 of about 14,637,537 (49)

FinnGen provides genetic insights from a well-phenotyped isolated population

open access: yesNature, 2023
Genome-wide association studies of individuals from an isolated population (data from the Finnish biobank study FinnGen) and consequent meta-analyses facilitate the identification of previously unknown coding variant associations for both rare and common
M. Kurki   +167 more
semanticscholar   +1 more source

Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer

open access: yesNature, 2023
Pancreatic ductal adenocarcinoma (PDAC) is lethal in 88% of patients^ 1 , yet harbours mutation-derived T cell neoantigens that are suitable for vaccines ^ 2 , 3 .
Luis A. Rojas   +50 more
semanticscholar   +1 more source

GWTC-3: Compact Binary Coalescences Observed by LIGO and Virgo during the Second Part of the Third Observing Run [PDF]

open access: yesPhysical Review X, 2021
The third Gravitational-Wave Transient Catalog (GWTC-3) describes signals detected with Advanced LIGO and Advanced Virgo up to the end of their third observing run.
The Ligo Scientific Collaboration   +499 more
semanticscholar   +1 more source

The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms

open access: yesLeukemia, 2022
We herein present an overview of the upcoming 5th edition of the World Health Organization Classification of Haematolymphoid Tumours focussing on lymphoid neoplasms.
R. Alaggio   +82 more
semanticscholar   +1 more source

Squidpy: a scalable framework for spatial omics analysis

open access: yesNature Methods, 2022
Spatial omics data are advancing the study of tissue organization and cellular communication at an unprecedented scale. Flexible tools are required to store, integrate and visualize the large diversity of spatial omics data.
G. Palla   +12 more
semanticscholar   +1 more source

Review of deep learning: concepts, CNN architectures, challenges, applications, future directions

open access: yesJournal of Big Data, 2021
In the last few years, the deep learning (DL) computing paradigm has been deemed the Gold Standard in the machine learning (ML) community. Moreover, it has gradually become the most widely used computational approach in the field of ML, thus achieving ...
Laith Alzubaidi   +9 more
semanticscholar   +1 more source

The 2021 WHO Classification of Tumors of the Central Nervous System: a summary.

open access: yesNeuro-Oncology, 2021
The fifth edition of the WHO Classification of Tumors of the Central Nervous System (CNS), published in 2021, is the sixth version of the international standard for the classification of brain and spinal cord tumors.
D. Louis   +12 more
semanticscholar   +1 more source

A saturated map of common genetic variants associated with human height

open access: yesNature, 2022
Common single-nucleotide polymorphisms (SNPs) are predicted to collectively explain 40–50% of phenotypic variation in human height, but identifying the specific variants and associated regions requires huge sample sizes1.
L. Yengo   +499 more
semanticscholar   +1 more source

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

open access: yesAutophagy, 2021
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field.
D. Klionsky   +499 more
semanticscholar   +1 more source

Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

open access: yesThe Lancet, 2021
Summary Background In this study, we aimed to evaluate the effects of tocilizumab in adult patients admitted to hospital with COVID-19 with both hypoxia and systemic inflammation.
O. Abani   +499 more
semanticscholar   +1 more source

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