Results 41 to 50 of about 110,664 (308)
, 2023 Matterport. (The VR reference space) plus recording. The next chapter in my artistic journey led to the creation of ARTeFACT, a living space meticulously crafted to capture a multitude of references and influences.
Delahunt, T.
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Examining the Philosophical Underpinnings of Design Science Research (DSR)
PhilosophiesDesign science research (DSR) has become a popular method in information systems research and has been warmly welcomed in other disciplines as well. The importance of DSR is evident, in terms of its contribution to knowledge, as well as the creation of ...
Chamara Panakaduwa +3 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Neural Network DDoS Mitigation System With Forensic Audit Support for Cyber Police
IEEE AccessThe article examines the timely and resource-efficient detection and neutralisation of the distributed DDoS attacks problem while simultaneously ensuring cryptographically reliable artefacting of evidence that meets the forensic suitability requirements.
Serhii Vladov +9 more
doaj +1 more source
Le « jeu non sérieux », une activité improductive ?
Interfaces Numériques, 2017 Cet article s’inscrit dans la lignée des travaux de Gilles Brougère et vise à étudier le rapport du jeu au sérieux. Sérieux est entendu au sens « utilitaire » comme le propose notamment Étienne Armand Amato.
Julian Alvarez +2 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
De gemeente Goes heeft het voornemen om de twee percelen aan de Oostmolenweg 10A en B te kopen. Voorafgaand aan de verkoop wil de gemeente de archeologische waarde van de percelen in kaart brengen.
Artefact! Advies en Onderzoek in Erfgoed
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source