Results 281 to 290 of about 74,638 (327)
Nature Medicine, 2020 Artemisinin resistance (delayed P. falciparum clearance following artemisinin-based combination therapy), is widespread across Southeast Asia but to date has not been reported in Africa1–4. Here we genotyped the P.
Barbara H Stokes +2 more
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High-level semi-synthetic production of the potent antimalarial artemisinin
Nature, 2013 Isabel C F R Ferreira
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Medicinal research reviews (Print), 2021
The sesquiterpene lactone artemisinin from Artemisia annua L. is well established for malaria therapy, but its bioactivity spectrum is much broader.
T. Efferth, F. Oesch
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The sesquiterpene lactone artemisinin from Artemisia annua L. is well established for malaria therapy, but its bioactivity spectrum is much broader.
T. Efferth, F. Oesch
semanticscholar +1 more source
Journal of Integrative Plant Biology, 2022
The important antimalarial drug artemisinin is biosynthesized and stored in Artemisia annua glandular trichomes and the artemisinin content correlates with trichome density; however, the factors affecting trichome development are largely unknown.
Zongyou Lv +9 more
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The important antimalarial drug artemisinin is biosynthesized and stored in Artemisia annua glandular trichomes and the artemisinin content correlates with trichome density; however, the factors affecting trichome development are largely unknown.
Zongyou Lv +9 more
semanticscholar +1 more source
New Phytologist, 2022
Artemisinin, a sesquiterpene lactone isolated from Artemisia annua L., is in huge market demand due to its efficient anti-malarial action, especially after the COVID-19 pandemic.
Mingyuan Yuan +8 more
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Artemisinin, a sesquiterpene lactone isolated from Artemisia annua L., is in huge market demand due to its efficient anti-malarial action, especially after the COVID-19 pandemic.
Mingyuan Yuan +8 more
semanticscholar +1 more source
, 2021
High power conversion efficiencies (PCEs) surpassing 20% have been achieved on flexible single-junction perovskite solar cells recently. However, improvements of the open-circuit voltage (VOC) and fill factor (FF), limited by the nonradiative ...
Longkai Yang +7 more
semanticscholar +1 more source
High power conversion efficiencies (PCEs) surpassing 20% have been achieved on flexible single-junction perovskite solar cells recently. However, improvements of the open-circuit voltage (VOC) and fill factor (FF), limited by the nonradiative ...
Longkai Yang +7 more
semanticscholar +1 more source
An Update on Artemisinin Resistance
2019While the precise mode of action of artemisinin (ART) derivatives remains obscure, it is nonetheless commonly accepted that ART generates reactive oxygen intermediates that contribute to cell death. Also, numerous studies confirm that point mutations in the propeller domain of K13 protein play a key role in resistance to ART derivatives. Because of its
Ariey, Frederic, Ménard, Didier
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Chemistry of artemisinin: an overview
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1994The endoperoxide sesquiterpene lactone, artemisinin, and its derivatives have become increasingly important as antimalarial drugs with impressive activity against multidrug resistant forms of Plasmodium falciparum. Artemisinin has a novel structure among known antimalarial compounds with a unique 1,2,4-trioxane ring that is essential for activity. This
Erich K. Lehnert, H.Kyle Webster
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Akupunktur & Aurikulomedizin, 2016
Der Pflanzeninhaltsstoff Artemisinin des Einjahrigen Beifus (Artemisia annua) ist durch die Verleihung des Medizinnobelpreises an die chinesische Forscherin Tu Youyou in den Fokus der Offentlichkeit geruckt. Die medizinische Verwendung der Pflanze weist eine lange Tradition auf.
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Der Pflanzeninhaltsstoff Artemisinin des Einjahrigen Beifus (Artemisia annua) ist durch die Verleihung des Medizinnobelpreises an die chinesische Forscherin Tu Youyou in den Fokus der Offentlichkeit geruckt. Die medizinische Verwendung der Pflanze weist eine lange Tradition auf.
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Unpacking ‘Artemisinin Resistance’
Trends in Pharmacological Sciences, 2017Artemisinin and its derivatives, in combination with partner drugs, are currently the most effective treatments for malaria parasite infection. Even though artemisinin has been widely used for decades, its mechanism of action had remained controversial until recently.
Jigang Wang +4 more
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