PURPOSE: It is increasingly common for health care professionals from developed countries to travel to developing regions of the world to learn or teach.
Drain +6 more
core +1 more source
Although the number of yearly occurrences of malaria has significantly decreased in recent years, malaria remains one of the major public health issues in Cameroon. A deeper understanding of how the various alleles of the malaria parasite’s genes move in the field between the two sexes and between seasons, as well as knowledge of malaria parasite ...
Che Roland Achungu +6 more
wiley +1 more source
Artesunate and artemether are effective fasciolicides in the rat model and in vitro [PDF]
Objectives: To study the fasciocidal properties of artesunate and artemether in the rat model and in vitro. Methods: Adult Fasciola hepatica were exposed in vitro to 1, 10 and 100 µg/mL of artesunate, artemether and dihydroartemisinin for 72 h.
Keiser, Jennifer +3 more
core
Intrarectal artemisinin derivatives.
The artemisinin derivatives are the most potent antimalarials. They are rapidly absorbed orally, parenterally and intra-rectally. The latter mode of administration is particularly interesting in rural tropics. Preliminary studies have shown that artemisinin and its derivatives artesunate and artemether are effective when given intrarectally.
Nosten, F, van Vugt, M, White, N
openaire +3 more sources
Adult triclabendazole-resistant Fasciola hepatica: morphological changes in the tegument and gut following in vivo treatment with artemether in the rat model [PDF]
A study has been carried out to determine the morphological changes to the adult liver fluke, Fasciola hepatica after treatment in vivo with artemether. Rats were infected with the triclabendazole-resistant Sligo isolate of F. hepatica, dosed orally with
Brennan, G.P. +5 more
core
Widespread Availability of Artemisinin Monotherapy in the United States
Robert M. Rakita, Uma Malhotra
doaj +1 more source
Efficacy and safety of artemether against a natural Fasciola hepatica infection in sheep [PDF]
Triclabendazole is the current drug of choice against Fasciola spp. infections in livestock, but resistance has become a major problem. In this study, we assessed the efficacy and safety of artemether, a derivative of artemisinin, in sheep with a low ...
Cringoli, Giuseppe +6 more
core
Shrinking the Malaria Map: A Prospectus on Malaria Elimination [PDF]
\ud Thirty-nine countries across the world are making progress toward malaria elimination. Some are committed to nationwide elimination, while others are pursuing spatially progressive elimination within their borders.
Feachem, Richard G.A. +2 more
core
Comparative study of the effects of artemether and artesunate on juvenile and adult Schistosoma mansoni in experimentally infected mice [PDF]
Artemether and artesunate, derivatives of the antimalarial artemisinin, also exhibit antischistosomal properties. There is a need to assess comparatively the activity of both compounds against different developmental stages of schistosome parasites ...
Chollet, Jacques +4 more
core
Preclinical Evaluation of Repurposed Antimalarial Artemisinins for the Treatment of Malignant Peripheral Nerve Sheath Tumors. [PDF]
Duensing HM +6 more
europepmc +1 more source

