Phenotypic and genotypic characterization of Thai isolates of Plasmodium falciparum after an artemisinin resistance containment project [PDF]
Thunyapit Thita +8 more
openalex +1 more source
Adult triclabendazole-resistant Fasciola hepatica: morphological changes in the tegument and gut following in vivo treatment with artemether in the rat model [PDF]
A study has been carried out to determine the morphological changes to the adult liver fluke, Fasciola hepatica after treatment in vivo with artemether. Rats were infected with the triclabendazole-resistant Sligo isolate of F. hepatica, dosed orally with
Brennan, G.P. +5 more
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Comparative study of the effects of artemether and artesunate on juvenile and adult Schistosoma mansoni in experimentally infected mice [PDF]
Artemether and artesunate, derivatives of the antimalarial artemisinin, also exhibit antischistosomal properties. There is a need to assess comparatively the activity of both compounds against different developmental stages of schistosome parasites ...
Chollet, Jacques +4 more
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Anaemia following Artemisinin-Based Combination Treatments of Uncomplicated Plasmodium falciparum Malaria in Children: Temporal Patterns of Haematocrit and the Use of Uncomplicated Hyperparasitaemia as a Model for Evaluating Late-Appearing Anaemia [PDF]
Akin Sowunmi +16 more
openalex +1 more source
Erratum: A single amino acid residue can determine the sensitivity of SERCAs to artemisinins [PDF]
Anne‐Catrin Uhlemann +10 more
openalex +1 more source
Intrarectal artemisinin derivatives.
The artemisinin derivatives are the most potent antimalarials. They are rapidly absorbed orally, parenterally and intra-rectally. The latter mode of administration is particularly interesting in rural tropics. Preliminary studies have shown that artemisinin and its derivatives artesunate and artemether are effective when given intrarectally.
Nosten, F, van Vugt, M, White, N
openaire +3 more sources
Electron microscopical study to assess the in vitro effects of the synthetic trioxolane OZ78 against the liver fluke, Fasciola hepatica [PDF]
Adult Fasciola hepatica were incubated for 48 h in vitro in the synthetic peroxide, OZ78 at a concentration of 100 μg/ml and then prepared for scanning and transmission electron microscopy. There was limited disruption to the external fluke surface, with
BRENNAN, G. P. +4 more
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Efficacy and safety of artemether against a natural Fasciola hepatica infection in sheep [PDF]
Triclabendazole is the current drug of choice against Fasciola spp. infections in livestock, but resistance has become a major problem. In this study, we assessed the efficacy and safety of artemether, a derivative of artemisinin, in sheep with a low ...
Cringoli, Giuseppe +6 more
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