Results 151 to 160 of about 17,496 (173)
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Comparison of 9-hydroxy-artemisinin with artemisinin: interaction with bovine hemoglobin
Journal of Luminescence, 2015Abstract In this article, the UV–vis absorption, steady state/time resolved fluorescence spectroscopy and synchronous fluorescence, circular dichrosim (CD) spectroscopy are used to investigate the interaction of artemisinin (QHS) and 9-hydroxy-artemisinin (9-OH QHS) with BHb, respectively.
Xiuxue Yuan +7 more
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Repurposing artemisinins as neuroprotective agents: a focus on the PI3k/Akt signalling pathway
Naunyn-Schmiedeberg's Archives of Pharmacology, 2022Richmond Arthur +2 more
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Birth defects research. Clinical and molecular teratology, 2012
Rat studies suggest that artemisinin-induced decreases in reticulocyte count are a marker for embryotoxicity (in one study, r = 0.82; p < 0.05). In clinical studies, therapeutic doses of artemisinins induced decreases in reticulocyte count that were ...
R. Clark
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Rat studies suggest that artemisinin-induced decreases in reticulocyte count are a marker for embryotoxicity (in one study, r = 0.82; p < 0.05). In clinical studies, therapeutic doses of artemisinins induced decreases in reticulocyte count that were ...
R. Clark
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2017
In the aforementioned chapters, newly marketed antimalarial drugs, artemisinin, and dihydroartemisinin that have been developed by the Institute of Chinese Material Medica, China Academy of Chinese Medical Sciences are described in details. This chapter will present a brief introduction to other marketed artemisinin-like drugs which have been developed
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In the aforementioned chapters, newly marketed antimalarial drugs, artemisinin, and dihydroartemisinin that have been developed by the Institute of Chinese Material Medica, China Academy of Chinese Medical Sciences are described in details. This chapter will present a brief introduction to other marketed artemisinin-like drugs which have been developed
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Functional Genomics and the Biosynthesis of Artemisinin
ChemInform, 2007AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Goska Nowak +4 more
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Photochemistry of Artemisinin Derivatives
Natural Product Letters, 1998Abstract Photochemical reactivity of some oxoalkyl derivatives of dihydroartemisinin as well as the reaction of dihydroartemisinin with lead tetraacetate/iodine under visible light have been studied.
Tran Duc Quan +4 more
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Targeted treatment of cancer with artemisinin and artemisinin-tagged iron-carrying compounds
Expert Opinion on Therapeutic Targets, 2005Artemisinin is a chemical compound that reacts with iron to form free radicals which can kill cells. Cancer cells require and uptake a large amount of iron to proliferate. They are more susceptible to the cytotoxic effect of artemisinin than normal cells.
Henry Lai +2 more
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Clinical Microbiology Reviews
SUMMARY The artemisinin antimalarials are the cornerstone of current malaria treatment. The development of artemisinin resistance in Plasmodium falciparum poses a major threat to malaria control and elimination.
N. J. White, K. Chotivanich
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SUMMARY The artemisinin antimalarials are the cornerstone of current malaria treatment. The development of artemisinin resistance in Plasmodium falciparum poses a major threat to malaria control and elimination.
N. J. White, K. Chotivanich
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Biotransformation of artemisinin by Aspergillus niger
Applied Microbiology and Biotechnology, 2015Biotransformation of artemisinin (1) by Aspergillus niger was investigated. During 12 days at 28 °C and pH 6.0, A. niger transformed artemisinin into four products. They were identified as 3β-hydroxy-4,12-epoxy-1-deoxyartemisinin (2), artemisinin G (3), 3,13-epoxyartemisinin (4), and 4α-hydroxy-1-deoxyartemisinin (5). Products 2 and 4 are new compounds
Pingying Wei +7 more
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Artemisinin and Its Derivatives
2001Artemisinin and its derivatives are endoperoxide-containing natural products that are being used widely as antimalarials in many parts of the world. The most commonly used artemisinin derivatives are artesunate, artemether, arteether, and dihydroartemisinin (Fig. 1). Artelinic acid (Fig. 1) (1) is currently in preclinical development.
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