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Nicotine Administration Augments Abdominal Aortic Aneurysm Progression in Rats
Inflammation and elastin degradation are key hallmarks in the pathogenesis of abdominal aortic aneurysms (AAAs). It has been acknowledged that activation of alpha7 nicotinic acetylcholine receptors (α7nAChRs) attenuates inflammation, termed the ...
Hana Hadzikadunic+7 more
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Symposium 2: New renal protection strategies in mellitus diabetes type 2
In recent years, the NKF National Kidney Foundation modified the term "diabetic nephropathy" which is only used for biopsy-confirmed pathology using the termof diabetic kidney disease (CKD) in order to understand that some patients with diabetes can have
Alicia Elbert
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Association between Inguinal Hernia and Arterial Disease: A Preliminary Report
Background: Inguinal hernia (IH) is a major problem in general surgery and its prevalence is increasing. The presence of hernias has been associated with a wide spectrum of venous diseases, with the involvement of imbalances in collagen and extracellular
Raffaele Serra+11 more
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Inflammation in arterial diseases [PDF]
AbstractThe pathophysiology of some inflammatory arterial diseases (such as vasculitis, atherogenesis and aneurysms) has been widely investigated in the last decades. Among different soluble molecules, proinflammatory cytokines (such as TNF‐α, IL‐1 and IL‐6) were shown to trigger critical pathways regulating these arterial diseases. Together with these
CARBONE, FEDERICO, MONTECUCCO, FABRIZIO
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Pathophysiology and Therapeutics of Thoracic Aortic Aneurysm in Marfan Syndrome
About 20% of individuals afflicted with thoracic aortic disease have single-gene mutations that predispose the vessel to aneurysm formation and/or acute aortic dissection often without associated syndromic features. One widely studied exception is Marfan
Keiichi Asano+3 more
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Approximately 25%–30% of patients diagnosed with idiopathic pulmonary arterial hypertension (PAH) have a clustered underlying Mendelian genetic cause and should be classified as heritable PAH (HPAH).
Kae‐Woei Liang+4 more
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Supervised exercise therapy (SET) is a conservative non-operative treatment strategy for improving walking performance in patients with peripheral artery disease (PAD).
Farahnaz Fallahtafti+5 more
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Understudied factors in drug‐coated balloon design and evaluation: A biophysical perspective
Drug‐coated balloon (DCB) percutaneous interventional therapy allows for durable reopening of the narrowed lumen via physical tissue expansion and local anti‐restenosis drug delivery, providing an alternative to traditional uncoated balloons or a ...
Tarek Shazly+5 more
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Peripheral artery disease [PDF]
### What you need to know Peripheral artery disease affects around 13% of the Western population who are more than 50 years old.1 It is most commonly due to atherosclerosis, where an atherosclerotic plaque causes arterial stenosis or occlusion. This results in a reduction in blood flow to the affected limb.
Anita Sharma+4 more
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