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Nicotine Administration Augments Abdominal Aortic Aneurysm Progression in Rats

open access: yesBiomedicines, 2023
Inflammation and elastin degradation are key hallmarks in the pathogenesis of abdominal aortic aneurysms (AAAs). It has been acknowledged that activation of alpha7 nicotinic acetylcholine receptors (α7nAChRs) attenuates inflammation, termed the ...
Hana Hadzikadunic   +7 more
doaj   +1 more source

Symposium 2: New renal protection strategies in mellitus diabetes type 2

open access: yesRevista de la Sociedad Argentina de Diabetes, 2022
In recent years, the NKF National Kidney Foundation modified the term "diabetic nephropathy" which is only used for biopsy-confirmed pathology using the termof diabetic kidney disease (CKD) in order to understand that some patients with diabetes can have
Alicia Elbert
doaj   +1 more source

Association between Inguinal Hernia and Arterial Disease: A Preliminary Report

open access: yesBiology, 2021
Background: Inguinal hernia (IH) is a major problem in general surgery and its prevalence is increasing. The presence of hernias has been associated with a wide spectrum of venous diseases, with the involvement of imbalances in collagen and extracellular
Raffaele Serra   +11 more
doaj   +1 more source

Inflammation in arterial diseases [PDF]

open access: yesIUBMB Life, 2015
AbstractThe pathophysiology of some inflammatory arterial diseases (such as vasculitis, atherogenesis and aneurysms) has been widely investigated in the last decades. Among different soluble molecules, proinflammatory cytokines (such as TNF‐α, IL‐1 and IL‐6) were shown to trigger critical pathways regulating these arterial diseases. Together with these
CARBONE, FEDERICO, MONTECUCCO, FABRIZIO
openaire   +5 more sources

Pathophysiology and Therapeutics of Thoracic Aortic Aneurysm in Marfan Syndrome

open access: yesBiomolecules, 2022
About 20% of individuals afflicted with thoracic aortic disease have single-gene mutations that predispose the vessel to aneurysm formation and/or acute aortic dissection often without associated syndromic features. One widely studied exception is Marfan
Keiichi Asano   +3 more
doaj   +1 more source

A cluster of heritable pulmonary arterial hypertension cases in a family with all three siblings carrying the same novel AQP1 c.273C>G variant‐a case report

open access: yesPulmonary Circulation, 2023
Approximately 25%–30% of patients diagnosed with idiopathic pulmonary arterial hypertension (PAH) have a clustered underlying Mendelian genetic cause and should be classified as heritable PAH (HPAH).
Kae‐Woei Liang   +4 more
doaj   +1 more source

Joint Angle Variability Is Altered in Patients with Peripheral Artery Disease after Six Months of Exercise Intervention

open access: yesEntropy, 2022
Supervised exercise therapy (SET) is a conservative non-operative treatment strategy for improving walking performance in patients with peripheral artery disease (PAD).
Farahnaz Fallahtafti   +5 more
doaj   +1 more source

Understudied factors in drug‐coated balloon design and evaluation: A biophysical perspective

open access: yesBioengineering & Translational Medicine, 2023
Drug‐coated balloon (DCB) percutaneous interventional therapy allows for durable reopening of the narrowed lumen via physical tissue expansion and local anti‐restenosis drug delivery, providing an alternative to traditional uncoated balloons or a ...
Tarek Shazly   +5 more
doaj   +1 more source

Peripheral artery disease [PDF]

open access: yesBMJ, 2018
### What you need to know Peripheral artery disease affects around 13% of the Western population who are more than 50 years old.1 It is most commonly due to atherosclerosis, where an atherosclerotic plaque causes arterial stenosis or occlusion. This results in a reduction in blood flow to the affected limb.
Anita Sharma   +4 more
openaire   +5 more sources

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