RA of EEAR inhibits TGF‐β1 ubiquitination and changes conformation by target binding TGF‐β1, regulating TGF‐β1/Smad2/3 signaling pathway. Thus it down‐regulated downstream protein expression, inhibited EMT and collagen deposition of ECM, in order to EEAR preventing PF in COPD.
Lingfeng Peng +6 more
wiley +1 more source
A low-cost hematologic biomarker for evaluating peripheral arterial disease risk: Derived neutrophil-lymphocyte ratio in NHANES 1999-2004 adults. [PDF]
Liu Q, Wu X, Shi J.
europepmc +1 more source
Thyroid Arterial Embolization for the Management of Benign and Malignant Thyroid Disease: A Systematic Review [PDF]
Hannelore I. Coerts +8 more
openalex +1 more source
Use of Endovascular and Combined Interventions in Obliterating Occlusive-Stenotic Arterial Diseases of the Lower Limbs [PDF]
O.F. Sovtus, Rostyslav Sabadosh
openalex +1 more source
Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction
This study explores the role adipose tissue (AT) phenotypes have in determining cardiovascular outcomes in an obesity‐related heart failure with preserved ejection fraction (HFpEF) model. Pharmacological induction of thermogenesis promoted resilience to HFpEF‐induced remodeling of AT and conferred cardioprotection. Surgical and genetic models confirmed
Jordan Jousma +11 more
wiley +1 more source
Algorithm for the Revascularization of Infrainguinal Arterial Disease. [PDF]
Joh JH.
europepmc +1 more source
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen +11 more
wiley +1 more source
Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen +11 more
wiley +1 more source
Procedural Utility, Reliability, and Success of Endovascular Intervention for Peripheral Arterial Disease Utilizing Transradial Access. [PDF]
Khraisat A +6 more
europepmc +1 more source

