Results 241 to 250 of about 1,109,885 (334)

Single‐Cell Metabolic Imaging Reveals Glycogen‐Driven Adaptations in Endothelial Cells

Advanced Science, EarlyView.
Single‐cell metabolic imaging of diabetes‐associated endothelial dysfunction by SRS microscopy reveals dynamic glycogen storage and its role in modulating metabolic adaptations under glucose starvation. Abstract Endothelial dysfunction (ED) is a defining feature of diabetes mellitus (DM) and a key contributor to many metabolic and cardiovascular ...
Rahuljeet S. Chadha, Benjamin Yang, Dongqiang Yuan, Edmund D. Kapelczak, Philip A. Kocheril, Alonso Tapia, Shivansh Mahajan, Adrian Colazo, Naseeb K. Malhi, Joseph A. Ambarian, Xuejing Liu, Tara A. TeSlaa, Zhen B. Chen, Lu Wei   +13 more
wiley   +1 more source

The Effect of Atmospheric Saturated Oxygen Combined With Intelligent Upper and Lower Limb Rehabilitation Training on Diabetic Lower Extremity Arterial Disease. [PDF]

J Diabetes Res
Liu ZB, Wang LC, Li Y, Zhao L, Zhu QX, Zhang HL, Li HL.   +6 more
europepmc   +1 more source

A Shape‐Adaptive, Performance‐Programmable, Self‐Healable and On‐Demand Destructible Robotic Skin via Self‐Strengthening Dynamic Silicone

Advanced Science, EarlyView.
Enabled by the distinctive inter‐ and intra‐chain siloxane exchange in commercially available silicones as the dielectric layer, the omni‐adaptive robotic skin (OmniAdapt) integrates multiple advanced functionalities: programmable sensing performance via the self‐stiffening dielectric material, application as BPM sensor, shape adaptivity for electronic
Wusha Miao, Lara S. Laamari, Jing Yu, Sanjay Schreiber, Lukas Heer, Jiacheng Cui, Jiayuan Huang, Hedan Bai   +7 more
wiley   +1 more source

Oxidized HDL status in hemodialysis patients with peripheral arterial disease: a pilot study. [PDF]

Arch Med Sci Atheroscler Dis
Kotani K, Matsubara D, Mukai H, Ogura M, Iwazu Y.   +4 more
europepmc   +1 more source

Inactivation of AXL in Cardiac Fibroblasts Alleviates Right Ventricular Remodeling in Pulmonary Hypertension

Advanced Science, EarlyView.
Pulmonary hypertension (PH) is a progressive condition with high morbidity and mortality, largely owing to right ventricular (RV) failure resulting from maladaptive remodeling. Our study provides strong evidence in support of a critical, detrimental role for AXL as a previously unrecognized determinant driving RV fibrotic pathology in PH.
Li‐Wei Wu, Min Chen, Chen‐Yu Jiang, Dai‐Ji Jiang, Xu Zhang, Xiao‐He Xu, Yi‐Wei Liu, Bei Feng, Lin‐Cai Ye, Yang‐Yang He, Xu Huang, Yi‐Chi Zhang, Xing‐Liang Zhou, Yi Shen, Tian‐Yu Liu, Li‐Jun Fu, Yi Yan, Hao Zhang   +17 more
wiley   +1 more source

The Role of High-Sensitivity Cardiac Troponin and Ischemia-Modified Albumin in Patients with Lower Extremity Peripheral Arterial Disease. [PDF]

Int J Mol Sci
Boc V, Blinc A, Boc A.
europepmc   +1 more source

The Tumor‐to‐Endothelial Transfer of FTO Promotes Vascular Remodeling and Metastasis in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
Integrated omics analysis of matched primary and liver metastatic NPC tumors reveals a unique NOTCH1+ CSC subpopulation exhibiting enhanced stemness properties and tumorigenic capacity. With in vitro and in vivo assays, exosomal transfer of tumor‐derived FTO from NOTCH1+ cells to the endothelium promotes vascular permeability and metastatic potential ...
Chun Wu, Xuefei Liu, Liwen Gu, Jingru Lian, Yuting Wang, Yixin Cheng, Lianhui Duan, Guanyin Huang, Siqi Chen, Boxi Zhao, Sailan Liu, Yufan Yang, Shuqian Zheng, Zijian Lu, Wanping Guo, Jianyang Hu, Wenjing Wang, Zhixiang Zuo, Haiqiang Mai, LinQuan Tang, Songfa Zhang, Feiqiu Wen, Xin Hong, Ling Guo   +23 more
wiley   +1 more source

Prevalence of peripheral arterial disease and associated factors among hypertensive patients attending two tertiary hospitals of Addis Ababa, Ethiopia. [PDF]

BMC Cardiovasc Disord
Jemal SK, Yesuf SA.
europepmc   +1 more source

Comparative study between lymphocyte-monocyte ratio and platelet-lymphocyte ratio: novel markers for critical limb ischemia in peripheral arterial disease

, 2019
Varsha Swamy, R. Raksha, Sriram Rajagopalan   +2 more
openalex   +2 more sources

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

Advanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang, Shuang Li, Man Li, Wenke Zhou, Jianqing Zhang, Zhenfu Wu, Zhaoqi Mao, Juan Wan, Xinhao Tang, Baoping Zheng, Qiang Liu, Zhendong Li, Xiaobing Jiang, Qingping Wu, Youfan Ye, Haijun Wang   +15 more
wiley   +1 more source