Results 241 to 250 of about 10,758,011 (382)

FOXQ1 Regulates Brain Endothelial Mitochondrial Function by Orchestrating Calcium Signaling and Cristae Morphology

Advanced Science, EarlyView.
FOXQ1 emerges as a master transcriptional regulator of brain endothelial metabolism, orchestrating mitochondrial function through dual control of calcium signaling and cristae organization. This study reveals that brain endothelial cells rely on oxidative phosphorylation rather than glycolysis alone, challenging the current metabolic paradigm and ...
Wenzheng Zou, Yuqing Lv, Lin Li, Shukui Zhang, Jiaqi Liang, Chengchao Wu, Enyu Huang, Jianwei Jiao, Jingjing Zhang   +8 more
wiley   +1 more source

Editorial: Cystic kidney diseases in children and adults: from diagnosis to etiology and back

Frontiers in Pediatrics
Lovro Lamot, Lovro Lamot, Ivana Vuković Brinar, Ivana Vuković Brinar, Margareta Fištrek Prlić, Bodo Beck   +5 more
doaj   +1 more source

Deciphering the Role and Mechanism of Decidual Monocyte‐Derived Macrophage Infiltration in Obstetric Antiphospholipid Syndrome at Single‐Cell Resolution

Advanced Science, EarlyView.
This study uncovers a novel mechanism and therapeutic targets in obstetric antiphospholipid syndrome (OAPS). Antiphospholipid antibody/ß2‐glycoprotein I complex boosts CCL2 and TNF‐α expression in decidual macrophages via TLR4‐NF‐κB. CCL2 accumulates on endothelial surfaces via ACKR1, recruiting monocyte‐derived CCR2+ macrophages, driving inflammation,
Rui Gao, Pingying Qing, Hanxiao Chen, Zhengyan Hu, Qiaoran Yang, Chenyang Lu, Huimin Liu, Rujun Zeng, Yuanting Tang, Fan Yu, Jinbiao Han, Xin Liao, Xun Zeng, Lang Qin   +13 more
wiley   +1 more source

Can a Moderate Physical Activity Program Delivered in Primary Care Improve the Ankle-Brachial Index in Patients with Asymptomatic Peripheral Arterial Disease? [PDF]

Cureus
Iana A, Folescu R, Gurgus D.
europepmc   +1 more source

Vascular Smooth Muscle Cells and Arterial Stiffening: Relevance in Development, Aging, and Disease.

Physiological Reviews, 2017
P. Lacolley, V. Regnault, P. Segers, S. Laurent   +3 more
semanticscholar   +1 more source

Coronary Artery Disease [PDF]

BMJ, 1960
openaire   +3 more sources

Lumbar Sympathectomy in End Stage Arterial Occlusive Disease

, 1976
Geun Eun Kim, Ibrahim M. Ibrahim, Anthony M. Imparato   +2 more
openalex   +2 more sources

Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation

Advanced Science, EarlyView.
LPS‐induced systemic inflammation increases glymphatic influx but delays cervical lymphatic drainage, accompanied by AQP4 depolarization and impaired glymphatic clearance. Enhancing cerebral blood flow via the inotropic agent levosimendan effectively restored AQP4 polarization, improving glymphatic flux and amyloid‐β clearance.
Ruoyu Zhao, Bin Sun, Pengju Wei, Yingying Sun, Qianyan He, Kejia Zhang, Jun Lu, Shoujun Zhu, Yi Yang, Zhenni Guo   +9 more
wiley   +1 more source

Pro-inflammatory markers as predictors of arterial thrombosis in aged patients with peripheral arterial disease post revascularization. [PDF]

Front Med (Lausanne)
Rodriguez Alvarez AA, Cieri IF, Boya MN, Patel S, Agrawal A, Ferreira SPS, Alli C, Sharma S, Dua A.   +8 more
europepmc   +1 more source

Epidemiology of peripheral arterial disease and critical limb ischemia in an insured national population.

Journal of Vascular Surgery, 2014
M. Nehler, S. Duval, Lihong Diao, B. Annex, W. Hiatt, K. Rogers, A. Zakharyan, A. Hirsch   +7 more
semanticscholar   +1 more source