Results 251 to 260 of about 10,758,011 (382)

Single Cell and Spatial Transcriptomics Define a Proinflammatory and Profibrotic Niche After Kidney Injury

Advanced Science, EarlyView.
By integrating single‐cell RNA sequencing and spatial transcriptomics, tenascin C (TNC) is unveiled as a central organizer of the proinflammatory and profibrotic niche in kidney fibrosis. TNC promotes macrophage activation through TLR4/NF‐κB signaling, leading to renal inflammation and fibrosis.
Li Li, Jinlin Liao, Yuxi Zhang, Zifu Yao, Junxin Huang, Kejia Wu, Lu Li, Yiling Peng, Haili Zhu, Xue Hong, Xi Liu, Lili Zhou, Fan Fan Hou, Haiyan Fu, Youhua Liu   +14 more
wiley   +1 more source

Epidemic of lower extremity peripheral arterial disease in China: current trends and future prediction. [PDF]

Front Cardiovasc Med
Yu J, Zhang Y, Zhang Q, Wang J, Gu A, Wei J, Zhang C.   +6 more
europepmc   +1 more source

Calcium Burden Assessment and Impact on Drug-Eluting Balloons in Peripheral Arterial Disease

Cardiovascular and Interventional Radiology, 2014
F. Fanelli, A. Cannavale, M. Gazzetti, P. Lucatelli, A. Wlderk, C. Cirelli, A. d’Adamo, F. Salvatori   +7 more
semanticscholar   +1 more source

Familial occurrence of intracranial arterial occlusive disease (Moyamoya) in neurofibromatosis [PDF]

, 1980
RobertP. Erickson, James O. Woolliscroft, RichardJ. Allen   +2 more
openalex   +1 more source

Regulation of Neuroinflammation by Microglial DUBA‐IRAK1‐IKKβ Signaling Loop

Advanced Science, EarlyView.
The protein levels of deubiquitinating enzyme A (DUBA) are rapidly upregulated in microglia after activation of Toll‐like receptor 4 (TLR4). In turn, DUBA potentiates TLR4‐induced proinflammatory signal transduction in microglia by stabilizing interleukin‐1 receptor activated kinase 1 (IRAK1) through K48 deubiquitination.
Zhenhu Zhu, Zhongding Li, Kate Lykke Lambertsen, Zijun Cao, Meng Chen, Yanqi Xu, Bettina Hjelm Clausen, Keshuo Jin, Yiting Lu, Fuqi Mei, Xue Du, Kangmin Chen, Huiyuan Bai, Xian Su, Bincheng Zhou, Baohua Liu, Ran Li, Chaoqun Wang, Yuhua Li, Xiang Cai, Dirk Schlüter, Weihong Song, Xu Wang   +22 more
wiley   +1 more source

Standard exercise test to assess peripheral arterial disease. [PDF]

, 1980
S. P. Laing, R M Greenhalgh
openalex   +1 more source

Adamts1 Exacerbates Post‐Myocardial Infarction Scar Formation via Mechanosensing of Integrin α8

Advanced Science, EarlyView.
Proposed mechanistic model of ADAMTS1‐ITGα8 mechanotransduction in post‐MI scar formation. Schematic illustration showing the mechanistic pathway by which endothelial cell (EC) derived Adamts1 regulates cardiac fibroblast activation through ITGα8‐mediated mechanotransduction following myocardial infarction (MI).
Chun‐Yan Kong, Zhen Guo, Yu‐Lan Ma, Ming‐Yu Wang, Hai‐Yang Ni, Pan Wang, Wen‐Jun Qiu, En‐Gui Wang, Zhou Li, Zheng Yang, Bo Shen, Qi‐Zhu Tang   +11 more
wiley   +1 more source

Impact of cilostazol on clinical outcomes in lower extremity arterial disease patients after angioplasty: A real-world analysis. [PDF]

PLoS One
Chang HY, Lin HW, Chen PW, Lin SH, Chao TH, Li YH.   +5 more
europepmc   +1 more source

Multiple progressive intracranial arterial occlusions (`moyamoya' disease)

, 1977
D J O'Sullivan, G. H. K. Lim, Paul Darveniza, Geoffrey L. Coffey   +3 more
openalex   +1 more source

Glabridin‐Gold(I) Complex as a Novel Immunomodulatory Agent Targeting TrxR and MAPK Pathways for Synergistic Enhancement of Antitumor Immunity

Advanced Science, EarlyView.
Complex 6d could promote tumor immunogenicity by targeting thioredoxin reductase (TrxR) and remodel immunosuppressive microenvironment by the mitogen‐activated protein kinase (MAPK) pathway inhibition simultaneously. This study provides a novel approach to develop metal immunomodulatory agents by designing gold complexes incorporating natural products,
Zhaoran Wang, Meiyu Wang, Qiong Chen, Mengshi Wang, Fuwei Li, Lin Lv, Zhenfan Wen, Zhongren Xu, Yixia Yang, Chunyang Bi, Wukun Liu   +10 more
wiley   +1 more source