Results 251 to 260 of about 10,664,685 (382)

Conservative drug treatment in patients with moderately severe chronic occlusive peripheral arterial disease. Scandinavian Study Group. [PDF]

open access: bronze, 1989
Folke Lindgärde   +6 more
openalex   +1 more source

Cardiovascular Disease Meets Cancer: Exploring the Epidemiology in China and Homotherapy Targeting Intersectional Mechanisms

open access: yesAdvanced Science, EarlyView.
Cardiovascular disease (CVD) and cancer are leading causes of death worldwide, with overlapping risk factors and pathophysiological mechanisms. This review explores shared pathways, including metabolic dysregulation, chronic inflammation, and gut microbiome alterations, highlighting dual‐benefit strategies such as lifestyle modifications and repurposed
Shihan Xiang   +6 more
wiley   +1 more source

THE PATHOLOGY OF ARTERIAL DISEASE

open access: yesBritish Journal of Anaesthesia, 1981
A.G. Maciver, P.J. Gallagher
openaire   +3 more sources

Glycolytic Enzyme HK2 Phosphorylates nSMase1 to Promote Astrocytic Exosomes Biogenesis Contributing to Acute Ischemic Stroke Injury

open access: yesAdvanced Science, EarlyView.
This study reveals that the glycolytic enzyme HK2 mediates hypoxia‐induced astrocytic exosome biogenesis by directly phosphorylating nSMase1. These astrocytic exosomes impair brain endothelial tight junctions. Astrocyte‐specific knockdown of HK2 reduces exosome release and alleviates brain injury after MCAO.
Chen Chen   +12 more
wiley   +1 more source

Temporal changes in symptomatic intracranial arterial disease: a longitudinal high-resolution vessel wall imaging study. [PDF]

open access: yesFront Neurol
Kang DW   +9 more
europepmc   +1 more source

Multiple progressive intracranial arterial occlusions (`moyamoya' disease)

open access: green, 1977
D J O'Sullivan   +3 more
openalex   +1 more source

Fluid Mechanics, Arterial Disease, and Gene Expression.

open access: yesAnnual Review of Fluid Mechanics, 2014
J. Tarbell   +3 more
semanticscholar   +1 more source

The GRK2/AP‐1 Signaling Axis Mediates Vascular Endothelial Dysfunction and Atherosclerosis Induced by Oscillatory Low Shear Stress

open access: yesAdvanced Science, EarlyView.
This study highlights GRK2 is a central mediator in OSS‐induced endothelial dysfunction. OSS activates GPCRs in endothelial cells, leading to GRK2 phosphorylation and the activation of AP‐1. AP‐1 induces inflammation, while also promoting NR4A1 expression and anchoring LKB1 in the nucleus, which suppresses AMPK activity. This cascade causes endothelial
Li‐Da Wu   +18 more
wiley   +1 more source

Home - About - Disclaimer - Privacy