Results 21 to 30 of about 568,907 (313)

Intradialytic Muscle Cramp and its Association with Peripheral Arterial Disease in End Stage Renal Disease Patients on Hemodialysis

Journal of Nepal Medical Association, 2014
Introduction: Muscle cramp is a common intradialytic complication observed in hemodialysis patients. Similarly Peripheral arterial disease is a common condition in the hemodialysis population.
Madhav Ghimire, Sanjib Kumar Sharma, Romila Chimoriya, Gopal Chandra Das   +3 more
doaj   +3 more sources

Arachidonic Acid, but Not Omega‐3 Index, Relates to the Prevalence and Progression of Abdominal Aortic Aneurysm in a Population‐Based Study of Danish Men

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundAnimal models support dietary omega‐3 fatty acids protection against abdominal aortic aneurysm (AAA), but clinical data are scarce. The sum of red blood cell proportions of the omega‐3 eicosapentaenoic and docosahexaenoic acids, known as omega ...
Jes S. Lindholt, Katrine L. Kristensen, Elena Burillo, Diego Martinez‐Lopez, Carlos Calvo, Emilio Ros, Jose L. Martín‐Ventura, Aleix Sala‐Vila   +7 more
doaj   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

The Cultural “Blood Ties” Between Medical Anthropology and Cardiovascular Disease: A Narrative Review

Societies
Background: Medical anthropology is a subfield that examines the various factors influencing health, disease, illness, and sickness. Cardiovascular disease (CVD) encompasses a range of disorders affecting the heart, arteries, and veins. Patients with CVD
Davide Costa, Raffaele Serra
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Novel risk factors for premature peripheral arterial occlusive disease in non-diabetic patients: a case-control study. [PDF]

PLoS ONE, 2013
BACKGROUND: This study aimed to determine the prevalence of genetic and environmental vascular risk factors in non diabetic patients with premature peripheral arterial disease, either peripheral arterial occlusive disease or thromboangiitis obliterans ...
Annie M Bérard, Aurélie Bedel, Rémi Le Trequesser, Geneviève Freyburger, Alan Nurden, Sylvie Colomer, Viviane Guérin, Marie-Christine Vergnes, François Becker, Gabriel Camelot, Luc Bressolette, Philippe Lacroix, Jean-Pierre Cambou, Alessandra Bura-Rivière, Joseph Emmerich, Michel Darmon, Anne-Marie Deletraz, Samir Mesli, Brigitte Colombies, Virginie Vanbrugghe, Claude Conri, Joël Constans   +21 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

Molecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren, Philippe Decruyenaere, Francisco Avila Cobos, Johanna Bult, Jill Deleu, Laudonia Lidia Dipalo, Hetty Hilde Helsmoortel, Eva Hulstaert, Annelien Morlion, Elena Ramos Varas, Kathleen Schoofs, Wim Trypsteen, Eveline Vanden Eynde, Hanne Van Droogenbroeck, Kimberly Verniers, Jo Vandesompele, Anneleen Decock   +16 more
wiley   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

Characterization of a new apolipoprotein E5 variant detected in two French-Canadian subjects

Journal of Lipid Research, 1991
We have found a novel apoE5 mutation, using isoelectric focusing (IEF), in two apparently unrelated French-Canadian subjects. Co-dominant inheritance was demonstrated in the family of the first proband, a healthy male subject.
F Mailly, CF Xu, M Xhignesse, S Lussier-Cacan, PJ Talmud, J Davignon, SE Humphries, AC Nestruck   +7 more
doaj