Results 41 to 50 of about 700,020 (239)

Irisin and Cardiometabolic Disorders in Obesity: A Systematic Review

open access: yesInternational Journal of Inflammation, 2023
Background. Overweight and obesity are global health issues, impacting a significant portion of young adults. Obesity is a complex condition influenced by genetics and environmental factors, leading to increased susceptibility to cardiovascular diseases (
Jorge da Silva Pinho-Jr   +6 more
doaj   +1 more source

Metformin reverses development of pulmonary hypertension via aromatase inhibition [PDF]

open access: yes, 2016
Females are more susceptible to pulmonary arterial hypertension than males, although the reasons remain unclear. The hypoglycemic drug, metformin, is reported to have multiple actions, including the inhibition of aromatase and stimulation of AMP ...
Dean, Afshan   +4 more
core   +2 more sources

PHARMACOLOGICAL CORRECTION OF CEREBRAL BLOOD FLOW DISTURBANCES IN WOMEN WITH ARTERIAL HYPERTENSION IN POSTMENOPAUSE

open access: yesРациональная фармакотерапия в кардиологии, 2015
Aim: to study cerebral blood flow and cholesterol metabolism in menopausal women with arterial hypertension (AH); to evaluate dynamics of cerebral blood flow parameters and plasma lipid concentrations in these patients during 6-month antihypertensive and
V. V. Yakusevich   +3 more
doaj   +1 more source

Transcription factors in the pathogenesis of pulmonary arterial hypertension—Current knowledge and therapeutic potential

open access: yesFrontiers in Cardiovascular Medicine, 2023
Pulmonary arterial hypertension (PAH) is a disease characterized by elevated pulmonary vascular resistance and pulmonary artery pressure. Mortality remains high in severe cases despite significant advances in management and pharmacotherapy.
Jakob Körbelin   +10 more
doaj   +1 more source

The molecular genetics and cellular mechanisms underlying pulmonary arterial hypertension [PDF]

open access: yes, 2012
Pulmonary arterial hypertension (PAH) is an incurable disorder clinically characterised by a sustained elevation of mean arterial pressure in the absence of systemic involvement.
Machado, Rajiv
core   +2 more sources

Residual risk identified in routine noninvasive follow-up assessments in pulmonary arterial hypertension

open access: yesERJ Open Research, 2023
Background The 2022 ESC/ERS guidelines on pulmonary hypertension recommend noninvasive risk assessments based on three clinical variables during follow-up in patients with pulmonary arterial hypertension (PAH).
Jonna Ostermann   +6 more
doaj   +1 more source

Vascular smooth muscle contraction in hypertension [PDF]

open access: yes, 2018
Hypertension is a major risk factor for many common chronic diseases, such as heart failure, myocardial infarction, stroke, vascular dementia and chronic kidney disease.
Alves-Lopes, Rheure   +6 more
core   +1 more source

Arterial stiffness and hypertension [PDF]

open access: yesClinical Hypertension, 2018
Measures of the functional and structural properties of blood vessels can be used to assess preclinical stage of vascular disorders. Recent experimental and population studies show that arterial stiffening precedes development of high blood pressure, and can be used to predict future cardiovascular events.
openaire   +4 more sources

Follow‐up of renal transplant recipients after acute COVID‐19—A prospective cohort single‐center study

open access: yesImmunity, Inflammation and Disease, 2021
Introduction Although most patients recover within several weeks after acute COVID‐19, some of them develop long‐lasting clinical symptoms. Renal transplant recipients have an increased mortality risk from COVID‐19.
Nikolina Basic‐Jukic   +7 more
doaj   +1 more source

Typical course of cystinuria leading to untypical complications in pregnancy: A case report and review of literature

open access: yesFrontiers in Medicine, 2023
Cystinuria is a rare genetic disorder inherited by an autosomal recessive pattern which affects the transmembrane transporter for the base amino acid cystine. It has a general prevalence of 1 in 7000 with demographic variations.
Ema Ivandic   +9 more
doaj   +1 more source

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