Cardiac sympathetic dysfunction in pulmonary arterial hypertension: Lesson from left-sided heart failure [PDF]
Sympathetic nervous system hyperactivity has a well-recognized role in the pathophysiology of heart failure with reduced left ventricular ejection fraction.
Bonaduce, Domenico+10 more
core +1 more source
Perivascular Inflammation in Pulmonary Arterial Hypertension
Perivascular inflammation is a prominent pathologic feature in most animal models of pulmonary hypertension (PH) as well as in pulmonary arterial hypertension (PAH) patients.
Yijie Hu+3 more
semanticscholar +1 more source
Romiplostim use in pregnant women with immune thrombocytopenia
Abstract Treatment for immune thrombocytopenia (ITP) in pregnancy is hampered by the lack of fetal safety evidence of maternally‐administered medications. The Pregnancy Surveillance Program (PSP) collected patient information from 2017–2020 for pregnancy, birth outcomes, and adverse events (AEs) for 186 women exposed to romiplostim from 20 days before ...
James B. Bussel+7 more
wiley +1 more source
Long-term therapy of interferon-alpha induced pulmonary arterial hypertension with different PDE-5 inhibitors: a case report [PDF]
BACKGROUND: Interferon alpha2 is widely used in hepatitis and high-risk melanoma. Interferon-induced pulmonary arterial hypertension as a side effect is rare.
Adrian C Borges+41 more
core +3 more sources
Maternal and fetal outcomes in pregnant women with pulmonary arterial hypertension: A single-center experience and review of current literature [PDF]
BACKGROUND: Although pregnancy in women with pulmonary arterial hypertension has been considered a high-risk condition, current data regarding pregnancy with pulmonary arterial hypertension are scarce.
Akbal, Özgür Yaşar+11 more
core +1 more source
Arterial stiffness and hypertension [PDF]
Measures of the functional and structural properties of blood vessels can be used to assess preclinical stage of vascular disorders. Recent experimental and population studies show that arterial stiffening precedes development of high blood pressure, and can be used to predict future cardiovascular events.
openaire +4 more sources
Bruton tyrosine kinase inhibitors in the management of Waldenström macroglobulinemia
Abstract Bruton tyrosine kinase (BTK) inhibitors have taken a central role in the management of patients with Waldenström macroglobulinemia and are the only agents approved by the Food and Drug Administration (FDA) to treat these patients. Although associated with high rates of durable responses, unmet needs with BTK inhibitor therapy include ...
Jorge J. Castillo+4 more
wiley +1 more source
The audiological profile of adults with and without hypertension [PDF]
OBJECTIVE: To determine whether there is any influence of systemic arterial hypertension on the peripheral auditory system. METHODS: This was a cross-sectional study that investigated 40 individuals between 30 and 50 years old, who were divided into ...
Matas, Carla Gentile+3 more
core +4 more sources
Risk stratification and medical therapy of pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) remains a severe clinical condition despite the availability over the past 15 years of multiple drugs interfering with the endothelin, nitric oxide and prostacyclin pathways.
N. Galiè+10 more
semanticscholar +1 more source
Arterial hypertension in adults. Clinical guidelines 2020
Arterial hypertension in adults.
Z. Kobalava+36 more
semanticscholar +1 more source