Results 91 to 100 of about 2,514,962 (302)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

open access: yesAdvanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao   +7 more
wiley   +1 more source

Elektrosonic Interference

open access: yes, 2001
A collaboration between The Arterial Group and San Francisco based performance artist Barry Schwartz at Brisbane Powerhouse Centre for Live Arts.\ud \ud Elektrosonic Interference combined large scale cinematic video projection, mechanical sound sculpture,
Schwartz, Barry, The Arterial Group
core  

Clinical Use of an Ultrasonic Doppler Flow Meter in Arterial Occlusive Diseases of the Lower Extremities [PDF]

open access: yes, 1975
1975-09Diagnostic value of a transcutaneous Doppler flow meter in arterial occlusive diseases was studied. Ankle systolic pressures at rest and after exercise were measured by placing a flow probe over the dorsalis pedis artery and posterior tibial ...
SHIONOYA, SHIGEHIKO   +2 more
core   +1 more source

Thermochemical Micro‐Explosion for Prompt Thrombolysis via Proximal Injection of Liquid Alkali Metal

open access: yesAdvanced Science, EarlyView.
We report a micro‐explosive thermochemical thrombolysis (METCT) therapy via injectable liquid alkali metal encapsulated in dimethyl silicone (LAM@oil). METCT enables prompt and safe vascular recanalization within 90 s. Critically, the LAM@oil system demonstrates significantly higher thrombolytic efficacy compared to clinically available thrombolytic ...
Xin Liao   +7 more
wiley   +1 more source

A Pathology‐Instructed Theranostic Platform with Mechanoadaptive and ROS‐Powered Nanobreathing Functions for Precision Myocardial Repair

open access: yesAdvanced Science, EarlyView.
We developed a pH responsive theranostic serum albumin hydrogel named BST, functionalized with MRI and CT probes and loaded with mitochondria targeted CAT‐SOD nanogels, that rapidly self repairs and mechanically stabilizes the infarcted myocardium, releases therapeutic nanogels and albumin under hypoxia induced acidosis to clear mitochondrial ROS ...
Zheng Luo   +7 more
wiley   +1 more source

Assessment of occlusive disease of lower extremity arteries on the basis of anatomic region: Value of 128-slice multidetector CT angiography in comparison with digital subtraction angiography

open access: yesJournal of College of Medical Sciences-Nepal, 2017
Background & Objectives: The Previous studies of multidetector CT (MDCT) of the lower extremities for the detection of peripheral vascular disease showed high diagnostic accuracy but were performed with older generation systems.
Roshan Pangeni   +6 more
doaj   +1 more source

Diagnostic reliability of the percutaneous ultrasonic Doppler technique for vertebral arterial occlusive diseases.

open access: yes, 1977
There is little data on the diagnostic reliability of the ultrasonic Doppler technique for vertebral arterial occlusive lesions. Percutaneous vertebral Doppler examination and the vertebral angiograms were compared to determine the diagnostic reliability
H Kaneda, T Irino, M Taneda, T Minami
core   +1 more source

Rocket‐Inspired Sequentially Targeted Nanotherapeutics for Mitochondrial Regulation and Inflammatory Reprogramming in Ischemic Stroke

open access: yesAdvanced Science, EarlyView.
A novel neutrophil‐hitchhiking, rocket‐inspired nanoplatform is developed to cross the blood‐brain barrier for sequential, spatiotemporal drug delivery. By responsive surface transformation in the ischemic penumbra, it precisely targets mitochondria to suppress Drp1‐mediated fission.
He Bai   +17 more
wiley   +1 more source

Erectile dysfunction of vascular cause: statistical evaluation on the Plurimetabolic Syndrome's risk factors and their correlation with penile eco-doppler rates.

open access: yesActa Médica Portuguesa, 2011
The Plurimetabolic Syndrome is a clustering of vascular risk factors (dyslipemia, abdominal perimeter, HTA and impaired glucose tolerance) with great importance in the development of cardiovascular disease (CVD) and diabetes (DM).
M Ferreira Coelho, P Bargão Santos
doaj   +1 more source

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