Results 81 to 90 of about 2,514,962 (302)

Parallel multiclass support vector interpretation of haemodynamic parameters for manifestation of aortic and arterial occlusive diseases

, 2013
Aortic and arterial occlusive diseases are congenital conditions manifested in impedance plethysmography and are difficult to interpret. A parallel multiclass support vector classification of haemodynamic parameters computed from plethysmographic ...
S. H. Karamchandani, S. N. Merchant, Karamchandani, S H, Desai, U B, Madan, V K, Kelkar, P M, V. K. Madan, U. B. Desai, Merchant, S N, P. M. Kelkar   +9 more
core   +1 more source

Aneurysmal disease is associated with lower carotid intima-media thickness than occlusive arterial disease [PDF]

, 2013
Objective: Patients with aneurysmal and occlusive arterial disease have overlapping cardiovascular risk profiles. The question remains how atherosclerosis is related to the formation of aortic aneurysms. Common carotid artery intima-media thickness (CIMT)
Luijtgaarden, K.M. (Koen) van de, Verhagen, Hence J.M., Rouwet, E.V. (Ellen), Verhagen, H.J.M. (Hence), Luijtgaarden, Koen, Hoeks, Sanne E., Valentijn, T.M. (Tabita), Majoor-Krakauer, D.F. (Danielle), van de Luijtgaarden, Koen M., Verhagen, Hence, Rouwet, Ellen V., Hoeks, Sanne; id_orcid, Stolker, Robert jan, Stolker, Robert J., Bakker, E.J. (Erik Jan), Valentijn, Tabita M., Bakker, EJ, Bakker, Erik J., Rouwet, Ellen, Hoeks, S.E. (Sanne), Stolker, R.J. (Robert), Majoor-Krakauer, Danielle, Majoor - Krakauer, Danielle, Valentijn, Tabita   +23 more
core   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

Percutaneous transluminal angioplasty and stenting for symptomatic intracranial atherosclerotic stenosis

Chinese Journal of Contemporary Neurology and Neurosurgery, 2010
Objective To evaluate the safety, efficacy, and short ⁃ and medium ⁃ term effect of percutaneous transluminal angioplasty and stenting (PTAS) for symptomatic intracranial atherosclerotic stenosis.
Hui⁃ming TIAN, Xiao⁃guang TONG, Wei⁃min KANG, Yan⁃guo SHANG, Tao SHUI   +4 more
doaj  

Optimal management of infrainguinal arterial occlusive disease

, 2014
David J Pennywell, Tze-Woei Tan, Wayne W Zhang Division of Vascular and Endovascular Surgery, Louisiana State University Health Shreveport, Shreveport, LA, USA Abstract: Peripheral arterial occlusive disease is becoming a major health problem in Western
Pennywell DJ, Zhang WW, Tan TW
core  

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source

Prevalence of peripheral occlusive arterial disease in patients with chronic renal failure [PDF]

, 2009
Background: Peripheral occlusive arterial disease has been found to be a sensitive marker of systemic atherosclerosis and a predictor of other cardiovascular diseases.
Aragão, Marina Elizabeth Cavalcanti de Sant’Anna, Reis, Francisco Prado, Borges Neto, Roberto Ribeiro, Nunes, Marco Antonio Prado, Feitosa, Vera Lúcia Corrêa, Aragão, José Aderval   +5 more
core  

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Pathophysiological mechanism, clinical classification and treatment strategy of acute progressive large vessel occlusive stroke

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Acute progressive large vessel occlusive stroke (APLVO) is a special kind of acute ischemic stroke with large vessel occlusion (AIS⁃LVO). Adequate medical history inquiry, detailed imaging analysis and appropriate individualized treatment can lead to ...
Yi⁃ming DENG, Jing⁃yu ZHANG, Xuan SUN, Li⁃gang SONG, Lian LIU, Xiao⁃chuan HUO, Da⁃peng MO, Ning MA, Feng GAO, Zhong⁃rong MIAO   +9 more
doaj  

Thymosin Alpha‐1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis

Advanced Science, EarlyView.
In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang, Shisi Wang, Liubin Zhang, Mengyan Hu, Xiaotao Su, Yuxin Liu, Qin Qin, Haotong Yi, Liling Yuan, Wei Cai, Lei Wei, Zhengqi Lu   +11 more
wiley   +1 more source