Results 61 to 70 of about 28,412 (248)

Escore para rastrear idosos (> 75 anos) de alto risco para doença arterial periférica A risk score for predicting peripheral arterial disease in individuals 75 years or older

Arquivos Brasileiros de Cardiologia, 2007
FUNDAMENTO: A prevalência de doença arterial periférica (DAP) é elevada entre os idosos. A maioria é assintomática e o exame físico pouco sensível. No Brasil, os fatores associados à DAP em idosos são pouco conhecidos.
Marcia Makdisse, Luiz Roberto Ramos, Frederico Moreira, Anderson Oliveira, Otavio Berwanger, Alcione Moscardi, Virginia Junqueira, Evandro Rodrigues, Antonio Carlos Carvalho   +8 more
doaj   +1 more source

Surgical intervention of Takayasu’s arteritis with supraaortic arterial occlusive disease and critical ischemia of upper extremity: A case report

, 2023
Caner Arslan, Yerik Junusbekov, Rauf Hamid   +2 more
openalex   +1 more source

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

Advanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu, Yajie Zhang, Yushi Tang, Hongli Hu, Ying Zhang, Junwen Xue, Hao Wang, Yecheng Wang, Chunfeng Liu, Jia Jia, Jian Cheng, Yongjun Cao   +11 more
wiley   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Clinical study on the effect of inflammation on severe stenosis or occlusion of intracranial and extracranial arteries

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To screen the risk factors for severe stenosis or occlusion of intracranial and extracranial arteries, and to explore the influence of inflammation on the location of intracranial and extracranial arteries stenosis or occlusion. Methods A total
Jun LI, Lei ZHAO, Wei FU, Jian WU
doaj  

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Analysis of endovascular treatment effects for anterior circulation large vessel occlusion caused by different etiologies

Chinese Journal of Contemporary Neurology and Neurosurgery
Objective To compare and analyze the clinical outcomes of endovascular treatment of anterior circulation large vessel occlusion (ac-LVO) caused by large artery atherosclerosis (LAA) and simple arterial embolization.
ZHOU Xing-chen, ZHAO Biao, WANG Da-wei, ZHANG Hui, WANG Hao, MIN Jing-liang   +5 more
doaj   +1 more source

Assessment of quality of life of patients with severe ischemia as a result of infrainguinal arterial occlusive disease [PDF]

, 1992
Maximiano Albers, Ayrton C. Fratezi, Nélson De Luccia   +2 more
openalex   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

Increased serum laminin and angiogenin concentrations in patients with peripheral arterial occlusive disease. [PDF]

, 1996
Heinz Burgmann, Ursula Hollenstein, Thomas Maca, Konstantin Zedwitz-Liebenstein, Florian Thalhammer, Renate Koppensteiner, H Ehringer, W. Graninger   +7 more
openalex   +1 more source