Short-term changes in cerebral perfusion based on three-dimensional arterial spin labeling after treatment of metformin-induced encephalopathy: a case description. [PDF]
Yang J +5 more
europepmc +1 more source
Genomic SEM of five ASCVD traits in > 3.8 million individuals identified 347 risk variants, including 19 novel loci. Integrating fine‐mapping and TWAS prioritized causal genes and revealed endothelial cell enrichment in vascular tissues. AI modelling shows the DCLRE1B mutation destabilizes the protein, impairing DNA repair and transcription.
Liwan Fu +4 more
wiley +1 more source
Arterial spin labeling MRI in assessing cerebral blood flow changes due to hypertension: a systematic review. [PDF]
Muthu SS +12 more
europepmc +1 more source
Luteolin‐7‐O‐β‐d‐glucuronide mitigates CS‐induced COPD progression by promoting cytokine‐mediated functional cross‐talk between alveolar macrophages and epithelial cells. ABSTRACT Chronic obstructive pulmonary disease (COPD) is associated with inflammation of the airway and lung parenchyma with limited airflow due to continued exposure to harmful ...
Jianhu Jia +13 more
wiley +1 more source
Three-dimensional pseudo-continuous arterial spin labeling magnetic resonance imaging: an effective imaging technique for early-stage kidney injury in patients with type 2 diabetes. [PDF]
Fang W +7 more
europepmc +1 more source
Diurnal Variations and Test–Retest Reliability of Resting‐State Functional MRI Metrics
Regional homogeneity (ReHo) exhibited the highest within‐day reliability, whereas fractional amplitude of low‐frequency fluctuations (fALFF) showed the lowest. The limbic network demonstrated the lowest reliability among the networks, with a notable mid‐morning dip at 10:00. ABSTRACT Resting‐state fMRI (rs‐fMRI) is widely used to assess intrinsic brain
Bowen Guo +12 more
wiley +1 more source
Prognostic value of arterial spin-labeling perfusion in anoxic brain injury: A retrospective cohort study. [PDF]
Beutler BD +9 more
europepmc +1 more source
Through a translational framework combining prospective dual‐center clinical cohorts with dextran sulfate sodium‐induced colitis models, this work integrated advanced neuroimaging, multi‐omics and neuromodulation interventions to redefine the high‐risk neurophenotype as a sustained pathogenic driver rather than a mere phenomenon, proposing brain‐gut ...
Xuehua Li +24 more
wiley +1 more source
Arterial spin labeling performs comparably to 2-[<sup>18</sup>F]fluoro-2-deoxy-D-glucose positron emission tomography for presurgical evaluation in pediatric lesional epilepsy. [PDF]
Gennari AG +7 more
europepmc +1 more source
S100A9 Aggravates Cardiac Fibrosis by TLR4/PGC‐1α Mediated Macrophage‐Myofibroblast Crosstalk
ABSTRACT Fibrosis is a critical component of ventricular remodelling after myocardial ischemia, and the activation and expansion of cardiac fibroblasts represent key drivers of this process. Our previous work identified S100A9‐dependent macrophage‐to‐myofibroblast transition (MMT) as a newly recognized source of myofibroblasts in the post‐MIR heart ...
Yiting Zhao +6 more
wiley +1 more source

