Results 81 to 90 of about 16,886 (302)

Diagnostic Potential of Pulsed Arterial Spin Labeling In Alzheimer's Disease

Frontiers in Neuroscience, 2016
Alzheimer’s disease (AD) is the most common cause of dementia. Although the underlying pathology is still not completely understood, several diagnostic methods are available. Frequently, the most accurate methods are also the most invasive.
Stefano eTrebeschi, Isabelle eRiederer, Christine ePreibisch, Peter Karl Bohn, Peter Karl Bohn, Stefan eFörster, Stefan eFörster, Panagiotis eAlexopoulos, Panagiotis eAlexopoulos, Claus eZimmer, Jan Stefan Kirschke, Alexander eValentinitsch   +11 more
doaj   +1 more source

ASL-BIDS, the brain imaging data structure extension for arterial spin labeling

Scientific Data, 2022
Arterial spin labeling (ASL) is a non-invasive MRI technique that allows for quantitative measurement of cerebral perfusion. Incomplete or inaccurate reporting of acquisition parameters complicates quantification, analysis, and sharing of ASL data ...
Patricia Clement, Marco Castellaro, Thomas W. Okell, David L. Thomas, Pieter Vandemaele, Sara Elgayar, Aaron Oliver-Taylor, Thomas Kirk, Joseph G. Woods, Sjoerd B. Vos, Joost P. A. Kuijer, Eric Achten, Matthias J. P. van Osch, BIDS maintainers, John A. Detre, Hanzhang Lu, David C. Alsop, Michael A. Chappell, Luis Hernandez-Garcia, Jan Petr, Henk J. M. M. Mutsaerts   +20 more
doaj   +1 more source

Recommendations for quantitative cerebral perfusion MRI using multi-timepoint arterial spin labeling: acquisition, quantification, and clinical applications

Accurate assessment of cerebral perfusion is vital for understanding the hemodynamic processes involved in various neurological disorders and guiding clinical decision-making.
Thomas, D.L., Golay, Xavier, Wang, D.J.J., Macintosh, B.J., Warnert, Esther A. H., Okell, T.W., Hernandez‐Garcia, Luis, Wang, Danny J., Okell, Thomas W, Osch, Matthias J.P. van, Ho, Mai-Lan, Achten, E., Qin, Qin, Zhao, Moss Y., Mutsaerts, Henk Jmm, Chappell, Michael A, Detre, John A, Dai, W.Y., Smits, Marion L.J., Warnert, E.A.H., Wang, Danny JJ, Parkes, Laura M, Zhao, M.S., Smits, Marion, Smits, M., Woods, Joseph G., Fan, A.P., Detre, John A., Osch, M.J.P. van, Fernández-Seara, M.A., Zelaya, Fernando; id_orcid, Warnert, Esther AH, Chappell, M.A., Okell, Thomas W., Fernández-Seara, María A., Madhuranthakam, Ananth J, Parkes, Laura M., Pinto, Joana, Wang, Danny J.J., Suzuki, Y., Fernández‐Seara, María A., Detre, J.A., Suzuki, Yuriko, Ho, Mai Lan, Ho, Mailan, Bolar, Divya S, Günther, M., Juttukonda, Meher R, Pinter, N., MacIntosh, Bradley J., Mutsaerts, H.J., Hernandez-Garcia, Luis, Fan, Audrey P, Günther, Matthias, Asllani, I., Smits, Marion; id_orcid, Mutsaerts, Henk‐Jan, Pinter, Nandor K., Juttukonda, Meher R., Pinto, J., Guo, J., Zelaya, Fernando O., Qin, Q., Thomas, David L, MacIntosh, Bradley J, Woods, Joseph G, ISMRM Perfusion Study Grp, Juttukonda, M.R., Zaharchuk, Greg, Van Osch, Matthias J.P., Parkes, Laura M.; id_orcid, Hernandez-Garcia, L., Warnert, Esther A.H., Mutsaerts, Henk-Jan, Parkes, L.M., Zaharchuk, G., Woods, J.G., Bolar, Divya S., Fan, Audrey P., Zelaya, Fernando, Van Osch, Matthias J. P., Wang, Danny J. J., Thomas, David L., Asllani, Iris, Madhuranthakam, Ananth J., Dai, Weiying, Zhao, Moss, Bolar, D.S., Zelaya, F., Ho, Mai‐Lan, Ho, M.L., Lu, H.Z., Golay, X., Madhuranthakam, A.J., the ISMRM Perfusion Study Group, Mutsaerts, Henk Jan, Lu, Hanzhang, Van Osch, Matthias JP, Chappell, Michael A., Achten, Eric, Fernández‐Seara, María A, Pinter, Nandor, Guo, Jia   +102 more
core   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Grading of skull base meningiomas by combined perfusion: arterial spin labeling and T2* dynamic susceptibility perfusion

The Egyptian Journal of Radiology and Nuclear Medicine
Background Conventional MRI has no distinction between high- and low-grade meningiomas, which has a crucial for choice of therapeutic plan, especially skull base meningiomas which need more meticulous endoscopy-approached surgery.
Lamya Eissa, Omneya Gamaleldin, Mohamed Hossameldin Khalifa   +2 more
doaj   +1 more source

Skeletal Muscle Microvascular Flow in Progressive Peripheral Artery Disease Assessment with Continuous Arterial Spin-Labeling Perfusion Magnetic Resonance Imaging

, 2010
Objectives We present the novel application of continuous arterial spin- labeling (CASL) magnetic resonance imaging ( MRI) for the measurement of calf muscle perfusion in subjects with progressive peripheral arterial disease (PAD).
吳文超, WU, WEN-CHAU
core  

Cholesterol Laundry of Cell Membrane and Fatty Liver by Detergent Liposomes to Improve Anti‐Cancer Drug Responsiveness of Patient Liver Tissues

Advanced Science, EarlyView.
Cholesterol‐enriched plasma membranes in hepatocellular carcinoma impede drug penetration. Cholesterol (+)‐liposomes act as membrane‐specific detergents, extracting cholesterol and reducing barrier function without cytotoxicity. Following endocytosis, cholesterol transfers from endosomes to liposomes and is metabolized in the ER.
Chansik Kim, Joo Kyung Noh, Sewoom Baek, Seung Eun Yu, Jueun Kim, Seongyo Lee, Youngji Oh, Dai Hoon Han, Seyong Chung, Hak‐Joon Sung   +9 more
wiley   +1 more source

Perfusion quantification by model-free arterial spin labeling using nonlinear stochastic regularization deconvolution. [PDF]

, 2013
Purpose: Quantification of cerebral blood flow can be accomplished by model-free arterial spin labeling using the quantitative STAR labeling of arterial regions (QUASAR) sequence.
Ronnie Wirestam, Knutsson, Linda, Linda Knutsson, André Ahlgren, Freddy Ståhlberg, Petersen, Esben Thade, Ahlgren, André, Wirestam, Ronnie, Ståhlberg, Freddy, Esben Thade Petersen   +9 more
core   +2 more sources

Additional Role of 3D ASL Perfusion in Skull Base Lesions

Indian Journal of Radiology and Imaging
Background Arterial spin labeling (ASL) perfusion imaging is widely used since its main advantage is that no intravenous contrast is needed.
J. Fairoze Naghath, S. Babu Peter
doaj   +1 more source

Prediction of early reperfusion from repeated arterial spin labeling perfusion magnetic resonance imaging during intravenous thrombolysis

, 2022
S.247-250Background and Purpose There are few in vivo data on the pathophysiology of reperfusion during systemic thrombolysis. We monitored the time course of cerebral perfusion changes in patients during thrombolysis with repeated arterial spin labeling
Gregori, J., Hennerici, M.G., Wolf, M.E., Griebe, M., Sauter-Servaes, J., Szabo, K., Günther, M., Okazaki, S., Gass, A., Kern, R.   +9 more
core   +1 more source