Interplay of integrins and selectins in metastasis
Molecular Oncology, EarlyView.Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva +2 more
wiley +1 more source
A coupling strategy for a 3D-1D model of the cardiovascular system to study the effects of pulse wave propagation on cardiac function [PDF]
arXiv, 2021 The impact of increased stiffness and pulsatile load on the circulation and their influence on heart performance have been documented not only for cardiovascular events but also for ventricular dysfunctions. For this reason, computer models of cardiac electromechanics (EM) have to integrate effects of the circulatory system on heart function to be ...
arxiv
Associations among different functional and structural arterial wall properties and their relations to traditional cardiovascular risk factors in healthy subjects: a cross-sectional study [PDF]
, 2012 BACKGROUND: The arterial wall possesses several functional and structural properties that define arterial health. Once they become impaired, cardiovascular risk increases.
Miodrag Janic +3 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objective Exploring the prevalence and association between intracranial atherosclerosis (ICAS) and cerebral small vessel diseases (CSVD), this study delved beyond the current scope, utilising high‐resolution vessel wall MRI (HRVW‐MRI) to investigate how subtle changes in intracranial atherosclerotic features influence the various burdens of ...
Joseph Amihere Ackah +6 more
wiley +1 more source
Photoplethysmography for the Assessment of Arterial Stiffness
Sensors, 2023 This review outlines the latest methods and innovations for assessing arterial stiffness, along with their respective advantages and disadvantages. Furthermore, we present compelling evidence indicating a recent growth in research focused on assessing arterial stiffness using photoplethysmography (PPG) and propose PPG as a potential tool for assessing ...
Parmis Karimpour +2 more
openaire +3 more sources
Probing blood pressure and arterial stiffness noninvasively by guided axial waves [PDF]
arXiv, 2020 The clinical and economic burden of cardiovascular diseases (CVDs) poses a global challenge. Growing evidence suggests an early assessment of arterial stiffness can provide insights into the pathogenesis of CVDs. However, it remains difficult to quantitatively characterize the arterial stiffness in vivo.
arxiv
Impact of diabetes mellitus on ventricular structure, arterial stiffness, and pulsatile hemodynamics in heart failure with preserved ejection fraction [PDF]
, 2019 Background-Heterogeneity in the underlying processes that contribute to heart failure with preserved ejection fraction (HFpEF) is increasingly recognized.
Akers, Scott R. +8 more
core +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives To investigate whether pulse pressure or mean arterial pressure mediates the relationship between age and white matter hyperintensity load and to examine the mediating effect of white matter hyperintensities on cognition. Methods Demographic information, blood pressure, current medication lists, and Montreal Cognitive Assessment ...
Jade Hannan +8 more
wiley +1 more source
Fractional-order Modeling of the Arterial Compliance: An Alternative Surrogate Measure of the Arterial Stiffness [PDF]
arXiv, 2020 Recent studies have demonstrated the advantages of fractional-order calculus tools for probing the viscoelastic properties of collagenous tissue, characterizing the arterial blood flow and red cell membrane mechanics, and modeling the aortic valve cusp.
arxiv
From arteries to boreholes: Transient response of a poroelastic cylinder to fluid injection [PDF]
Proceedings of the Royal Society A 474, 20180284 (2018), 2017 The radially outward flow of fluid through a porous medium occurs in many practical problems, from transport across vascular walls to the pressurisation of boreholes in the subsurface. When the driving pressure is non-negligible relative to the stiffness of the solid structure, the poromechanical coupling between the fluid and the solid can control ...
arxiv +1 more source