Results 121 to 130 of about 65,617 (244)

Pharmacological management of dyslipidemia in high and very high cardiovascular risk patients

Revista Española de Sanidad Penitenciaria
Dyslipaemia is one of the main risk factors in the development of cardiovascular diseases. Currently, there are different alternatives available (amongst which statins occupy a pre-eminent place), to optimise the treatment of patients at high or very ...
V. Pascual Fuster
doaj  

Hydrogel‐based drug delivery systems for intracerebral hemorrhage with therapeutic advances and emerging roles of the bone–brain axis

Interdisciplinary Medicine, Volume 4, Issue 4, July 2026.
Hydrogel‐based drug delivery systems offer a promising approach for treating intracerebral hemorrhage (ICH) by overcoming blood‐brain barrier limitations, enabling precise, sustained release of neuroprotective and anti‐inflammatory agents. These systems enhance treatment efficacy, but challenges remain in biosafety, drug penetration, and scalability ...
Haojun Shi, Min Chen, Yisheng Chen, MengYao Li, Jiale Ma, Zuozhen Yin, Li Wu, YangBao Miao, Zemin Ou, Ke Wu, Zhijie Xu, Lizhi Li, Shaocong Zhao, Shiwei He, Bin Huang, Guanwen He, Guanghui Wu, John H. Zhang, Liang Shi   +18 more
wiley   +1 more source

First Revision of the Guidelines for the Diagnosis and Management of Remethylation Disorders

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT This guideline summarizes diagnostic and therapeutic approaches based on a systematic literature review and evidence evaluation using the GRADE methodology. Given the limited high‐quality data, expert consensus was additionally obtained through a modified Delphi process.
Giorgia Olivieri, Andrea Bordugo, Birute Burnyte, Alessandro Costetti, Maria‐Luz Couce, Luisa Diogo, Francois Feillet, D. Sean Froese, Benedetta Greco, Jean‐Louis Gueant, Luciana Hannibal, Friederike Hörster, Viktor Kožich, Giancarlo La Marca, Irini Manoli, Fanny Mochel, Lorenzo Orazi, Belén Pérez, Manuel Schiff, Bernd C. Schwahn, Ida Schwartz, Karolina M. Stepien, Jolanta Sykut‐Cegielska, Trine Tangeraas, Rolf H. Zetterström, Carlo Dionisi‐Vici, Martina Huemer   +26 more
wiley   +1 more source

Improving Scientific Research: Renegotiated Principles of Science, Proposals, Failures, and Successes

European Journal of Clinical Investigation, Volume 56, Issue 7, July 2026.
ABSTRACT Science is a self‐correcting process, and scientific research aims to improve adequacy, accuracy, and utility. However, improving scientific research is a demanding task, especially when currently some key principles of science are challenged and renegotiated.
John P. A. Ioannidis
wiley   +1 more source

Multi‐Omics Landscape of Paraspinal Muscles in Spinal Muscular Atrophy With Scoliosis

Journal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
ABSTRACT Most spinal muscular atrophy (SMA) patients develop severe scoliosis by late adolescence. Given that the paraspinal muscles—particularly the multifidus—are indispensable for maintaining spinal stability, their site‐specific multi‐omics characteristics in SMA remain insufficiently defined. Herein, integrated multi‐omics sequencing was performed
Zhen Wang, Junduo Zhao, Xu'an Huang, Weiyun Chen, Jianxiong Shen   +4 more
wiley   +1 more source

Ciclo celular y arteriosclerosis inducida por la dieta [PDF]

, 2009
Ciclo celular y arteriosclerosis inducida por la ...
Andrés García, Vicente
core   +1 more source

Improved prognosis prediction of all‐cause mortality and cardiovascular events by combined assessment of both ankle‐brachial index and brachial‐ankle pulse wave velocity in individuals with diabetes: The Kyushu prevention study for atherosclerosis, a prospective, multicenter survey

Journal of Diabetes Investigation, Volume 17, Issue 7, Page 1172-1182, July 2026.
A novel algorithm combining ABI and baPWV was developed to predict mortality and CVD risk in individuals with diabetes. This algorithm improved the accuracy of mortality and CVD risk assessment and was independent from the Framingham Risk Score. ABSTRACT Aims/Introduction People with diabetes exhibit early‐stage cardiovascular disease (CVD).
Erina Eto, Yasutaka Maeda, Noriyuki Sonoda, Hajime Nawata, Ryoichi Takayanagi, Michio Shimabukuro, Toyoshi Inoguchi   +6 more
wiley   +1 more source

Inducible Nitric Oxide Synthase Suppresses the Development of Allograft Arteriosclerosis [PDF]

, 2014
In cardiac transplantation, chronic rejection takes the form of an occlusive vasculopathy. The mechanism underlying this disorder remains unclear. The purpose of this study was to investigate the role nitric oxide (NO) may play in the development of ...
Imre Kovesdi, Larry L. Shears Ii, Simon C. Watkins, Timothy R. Billiar, Nobuyoshi Kawaharada, Si M. Pham, Alena Lizonova, Edith Tzeng   +7 more
core  

Incremental values of AOPP, IL-6, and GDF15 for identifying arteriosclerosis in patients with obstructive sleep apnea

European Journal of Medical Research
Background The objective of this study was to determine the independent and incremental values of advanced oxidative protein product (AOPP), interleukin 6 (IL-6), and growth differentiation factor 15 (GDF15) in identifying arteriosclerosis in patients ...
Xinxin Li, Wen Liu, Yonghuai Wang, Cuiting Zhao, Qing Zhu, Zhishuang Dong, Chunyan Ma   +6 more
doaj   +1 more source

Mönckeberg’s sclerosis — one disease, different faces

Acta Angiologica
Cardiovascular diseases (CVDs) are a leading cause of global morbidity and mortality, affecting millions annually. Among the diverse spectrum of CVDs, Mönckeberg’s arteriosclerosis, a form of arterial calcification, poses unique challenges and clinical ...
Olgierd Dróżdż, Marcin Dołęga, Piotr Gacka, Julia Szymonik, Bartosz Wilczyński, Maria Lasocka, Gabriela Augustynowicz, Natalia Dolata, Anastasiia Pylypchuk, Joanna Bober, Katarzyna Madziarska   +10 more
doaj   +1 more source