Results 1 to 10 of about 130,307 (169)

Intracranial Arteriosclerosis Is Not Associated With Cerebral Amyloid Deposition [PDF]

Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring
BACKGROUND Intracranial arteriosclerosis and cerebral amyloid beta (Aβ) are both involved in the etiology of Alzheimer's disease (AD) dementia, but the direct link between these two pathologies remains elusive.
Julia Neitzel, Daniel Bos, Vernooij Meike   +2 more
exaly   +8 more sources

Hypertension, Intracranial Arteriosclerosis, and Structural Brain Changes in Patients With TIA or Ischemic Stroke [PDF]

European Stroke Journal
Abstract Background Hypertension is a major risk factor of structural brain changes, including atrophy and cerebral small vessel disease. Intracranial arteriosclerosis could be an underlying mechanism between hypertension and structural brain changes.
Daniel Bos, Brian B P Berghout, Bob Roozenbeek   +2 more
exaly   +8 more sources

Prognostic Impact of Intracranial Arteriosclerosis Subtype After Endovascular Treatment for Acute Ischaemic Stroke [PDF]

European Journal of Neurology
AbstractBackground and PurposeThe influence of intracranial arteriosclerosis (ICAR) on acute ischaemic stroke (AIS) prognosis is unclear. This study explored its impact, focusing on ICAR subtypes categorized by intracranial carotid artery calcification (ICAC) patterns: intimal or atherosclerotic versus internal elastic lamina calcification or non ...
Daniel Bos, Alicia Sierra, Gonzalo Valle-Peñacoba   +2 more
exaly   +9 more sources

Intracranial arterial calcification and cerebrovascular function in the general aging population – A 7T MRI Study [PDF]

Cerebral Circulation - Cognition and Behavior
Background: Intracranial arteriosclerosis may impair downstream cerebrovascular function, but the underlying mechanisms remain unclear. Using 7T MRI, we investigate the association between intracranial arteriosclerosis and cerebrovascular function in the
Anna M. Streiber, Carmen Kuenen, Stanley D.T. Pham, Julia Neitzel, Daniel Bos, Jeroen C.W. Siero, Jaco J.M. Zwanenburg, Nikki Dieleman, Geert Jan Biessels, Meike W. Vernooij   +9 more
doaj   +3 more sources

Angiography-derived fractional flow and clinical outcomes in symptomatic intracranial atherosclerotic stenosis [PDF]

Frontiers in Neurology
BackgroundTo explore the association between fractional flow (FF) and clinical outcomes in patients with symptomatic intracranial atherosclerotic stenosis (ICAS), and to evaluate its potential role in patient stratification.MethodsThis retrospective ...
Wanning Zheng, Wanning Zheng, Rong Zou, Ming Wang, Ming Wang, Ming Wang, Jiahao Tang, Jiahao Tang, Ruilin Chen, Ruilin Chen, Chaobo Zheng, Chaobo Zheng, Jie Gong, Jie Gong, Yuhai Gao, Yuhai Gao, Ning Wang, Ning Wang, Yuning Lu, Yuning Lu, Jiong Wu, Jiong Wu, Jens Fiehler, Adnan H. Siddiqui, Jianping Xiang, Shu Wan, Shu Wan, Shu Wan   +27 more
doaj   +2 more sources

Association of the Discordance Between Apolipoprotein B and Low‐Density Lipoprotein Cholesterol With Cognition [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background This study aimed to investigate and validate the association of the discordance between apoB (apolipoprotein B) and low‐density lipoprotein cholesterol (LDL‐C) or non–high‐density lipoprotein cholesterol with cognitive function and explore the
Jiwei Jiang, Chao Li, Yanli Zhang, Jie Liu, Yang Liu, Wenyi Li, Qiwei Ren, Huiying Zhang, Yunyun Duan, Qianting Lv, Huaguang Zheng, Yuesong Pan, Yu Tian   +12 more
doaj   +2 more sources

Ventriculomegaly without elevated intracranial pressure? Normal pressure hydrocephalus as a disorder of the cerebral windkessel [PDF]

Frontiers in Neurology
ObjectiveNormal pressure hydrocephalus (NPH) is characterized by ventriculomegaly without elevations in intracranial pressure (ICP). One way of viewing hydrocephalus is as a disorder of the cerebral windkessel.
Racheed Mani, Racheed Mani, Jade Basem, Liu Yang, Liu Yang, Nahid Shirdel Abdolmaleki, Anand Ravishankar, Susan Fiore, Petar Djuric, Michael Egnor   +9 more
doaj   +2 more sources

Impact of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors on intracranial atherosclerotic plaque characteristics and low density lipoprotein-cholesterol (LDL-C) reduction: a real-world observational study [PDF]

PeerJ
Background and purpose The combination of PCSK9 inhibitors and moderate statin therapy effectively stabilizes intracranial atherosclerotic plaques in patients with intracranial atherosclerotic stenosis (ICAS).
Zhenzhen Li, Xiaohui Li, Yiting Zhang, Jingwen Qi, Lifan Ji, Shuo Li, Mengmeng Gu, Yukai Liu, Yuqiao Zhang, Yanping Mei, Meng Wang, Junshan Zhou, Mouxiao Su, Lin Zhu, Qiwen Deng   +14 more
doaj   +3 more sources

Endovascular Treatment of Large Vessel Occlusion Strokes Due to Intracranial Atherosclerotic Disease [PDF]

Journal of Stroke, 2022
Mechanical thrombectomy (MT) has become the gold-standard for patients with acute large vessel occlusion strokes (LVOS). MT is highly effective in the treatment of embolic occlusions; however, underlying intracranial atherosclerotic disease (ICAD ...
Jin Soo Lee, Seong-Joon Lee, Ji Man Hong, Francisco José Arruda Mont Alverne, Fabricio Oliveira Lima, Raul G. Nogueira   +5 more
doaj   +1 more source

Diagnostic and Therapeutic Strategies for Acute Intracranial Atherosclerosis-related Occlusions [PDF]

Journal of Stroke, 2017
Intracranial atherosclerosis-related occlusion (ICAS-O) is frequently encountered at the time of endovascular revascularization treatment (ERT), especially in Asian countries. However, because baseline angiographic findings are similar between ICAS-O and
Jin Soo Lee, Ji Man Hong, Jong S. Kim
doaj   +1 more source