Intracranial arteriosclerosis is not associated with cerebral amyloid deposition [PDF]
Alzheimer's and Dementia: Diagnosis, Assessment and Disease MonitoringBACKGROUND Intracranial arteriosclerosis and cerebral amyloid beta (Aβ) are both involved in the etiology of Alzheimer's disease (AD) dementia, but the direct link between these two pathologies remains elusive.
Daniel Bos, Anna Maria Streiber
exaly +8 more sources
Hypertension, intracranial arteriosclerosis, and structural brain changes in patients with TIA or ischemic stroke [PDF]
European Stroke JournalAbstract Background Hypertension is a major risk factor of structural brain changes, including atrophy and cerebral small vessel disease. Intracranial arteriosclerosis could be an underlying mechanism between hypertension and structural brain changes.
Daniel Bos +2 more
exaly +8 more sources
Prognostic impact of intracranial arteriosclerosis subtype after endovascular treatment for acute ischaemic stroke [PDF]
European Journal of NeurologyAbstractBackground and PurposeThe influence of intracranial arteriosclerosis (ICAR) on acute ischaemic stroke (AIS) prognosis is unclear. This study explored its impact, focusing on ICAR subtypes categorized by intracranial carotid artery calcification (ICAC) patterns: intimal or atherosclerotic versus internal elastic lamina calcification or non ...
Daniel Bos, Alicia Sierra
exaly +9 more sources
Variations in intracranial arterial anatomy of the circle of Willis and their association with arteriosclerosis in patients with ischemic cerebrovascular disease [PDF]
International Journal of StrokeIntroduction: An estimated 20–31% of all people are born with a textbook anatomical configuration of the intracranial arteries comprising the Circle of Willis. Individuals with specific anatomical variants may be at elevated risk of intracranial arteriosclerosis, and possibly its sequelae of stroke and dementia,
Daniel Bos, Brian Berghout
exaly +8 more sources
Intracranial arteriosclerosis is related to cerebral small vessel disease: a prospective cohort study [PDF]
Neurobiology of Aging, 2021 Intracranial arteriosclerosis has been increasingly recognized as a risk factor for cognitive impairment and even dementia. A possible mechanism linking intracranial arteriosclerosis to cognitive impairment and dementia involves structural brain changes including cerebral small vessel disease (CSVD).
Maryam Kavousi +2 more
exaly +7 more sources
Morphological Subtypes of Intracranial Internal Carotid Artery Arteriosclerosis and the Risk of Stroke [PDF]
Stroke, 2022 Background: Accumulating evidence highlights the existence of distinct morphological subtypes of intracranial carotid arteriosclerosis. So far, little is known on the prevalence of these subtypes and subsequent stroke risk in the general population.
Ali C Akyildiz +2 more
exaly +10 more sources
Intracranial Carotid Arteriosclerosis Mediates the Association Between Blood Pressure and Cerebral Small Vessel Disease [PDF]
Hypertension, 2023 Background: Intracranial arteriosclerosis could explain the association between blood pressure (BP) and cerebral small vessel disease (CSVD). Therefore, we tested whether intracranial carotid artery calcification (ICAC) mediates the association between BP and CSVD and determined pathophysiological mechanisms ...
Daniel Bos, Jesus Melgarejo
exaly +8 more sources
Intracranial arterial calcification and cerebrovascular function in the general aging population – A 7T MRI Study [PDF]
Cerebral Circulation - Cognition and BehaviorBackground: Intracranial arteriosclerosis may impair downstream cerebrovascular function, but the underlying mechanisms remain unclear. Using 7T MRI, we investigate the association between intracranial arteriosclerosis and cerebrovascular function in the
Anna M. Streiber +9 more
doaj +3 more sources
Subtypes of Intracranial Carotid Arteriosclerosis and Vascular Prognosis in Chronic Kidney Disease Patients [PDF]
Kidney DiseasesIntroduction: Vascular calcification, linked to atherosclerosis, is a significant cardiovascular risk factor in chronic kidney disease (CKD).
Bo-Ching Lee +5 more
doaj +4 more sources
Intracranial arteriosclerosis and the risk of dementia: A population‐based cohort study [PDF]
Alzheimer's & Dementia, 2023 AbstractBACKGROUNDThe impact of intracranial arteriosclerosis on dementia remains largely unclear.METHODSIn 2339 stroke‐free and dementia‐free participants (52.2% women, mean age 69.5 years) from the general population, we assessed intracranial carotid artery calcification (ICAC) and vertebrobasilar artery calcification (VBAC) as proxy for ...
van den Beukel, TC +7 more
openaire +3 more sources