Results 11 to 20 of about 65,591 (217)

99mTechnetium-labeled low density lipoprotein: receptor recognition and intracellular sequestration of radiolabel.

Journal of Lipid Research, 1991
99MTechnetium-labeled low density lipoprotein (99MTc-labeled LDL) was developed to detect atherosclerosis by external imaging with the gamma scintillation camera (Lees, et al. J. Nucl. Med. 1985. 26: 1056-1062; Lees, et al. Arteriosclerosis. 1988. 8: 461-
AM Lees, RS Lees
doaj   +1 more source

Studies on the regulation of plasma cholesterol levels in squirrel monkeys of two genotypes

Journal of Lipid Research, 1972
Certain individual squirrel monkeys (“hyporesponders”) are able to remain normocholesterolemic when fed diets containing cholesterol (0.5 mg/kcal). Other squirrel monkeys (“hyperresponders”) when fed the same diet become hypercholesterolemic. The purpose
Hugh B. Lofland, Jr., Thomas B. Clarkson, Richard W. St. Clair, Noel D.M. Lehner   +3 more
doaj   +1 more source

Statin's role on blood pressure levels: Meta‐analysis based on randomized controlled trials

The Journal of Clinical Hypertension, 2023
Statins have been proven to be effective in minimizing the risk of cardiovascular adverse events, however, their effect on BP variability is debatable with respect to their significance and their use as a potential anti‐hypertensive.
Hui Ting Liu, Nian Hua Deng, Ze Fan Wu, Zhan Yang Zhou, Zhen Tian, Xi Yan Liu, Yan Xia Wang, Hong Yu Zheng, Yang Shao Ou, Zhi Sheng Jiang   +9 more
doaj   +1 more source

Peroxisome proliferator-activated receptor α polymorphisms and postprandial lipemia in healthy men

Journal of Lipid Research, 2007
Peroxisome proliferator-activated receptor α (PPARα) is a ligand-dependent transcription factor that plays a key role in lipid and glucose homeostasis. This study evaluated whether variants of PPARα are associated with postprandial lipemia. Subjects were
Toshiko Tanaka, Jose M. Ordovas, Javier Delgado-Lista, Francisco Perez-Jimenez, Carmen Marin, Pablo Perez-Martinez, Purificacion Gomez, Jose Lopez-Miranda   +7 more
doaj   +1 more source

Sex-specific association between carotid atherosclerosis and fundus arteriosclerosis in a Chinese population: a retrospective cross-sectional study

European Journal of Medical Research, 2023
Objectives Vascular stiffening is highly predictive of major adverse cardiovascular events. It is not clear whether microangiopathy, such as fundus arteriosclerosis, is related to carotid atherosclerosis. Hence, this study was designed to investigate the
Chunxing Liu, Xiaolong Yang, Mengmeng Ji, Xiaowei Zhang, Xiyun Bian, Tingli Chen, Yihan Li, Xing Qi, Jianfeng Wu, Jing Wang, Zaixiang Tang   +10 more
doaj   +1 more source

The HIV protease inhibitor ritonavir increases lipoprotein production and has no effect on lipoprotein clearance in mice

Journal of Lipid Research, 2002
This study examined the effect of human immunodeficiency virus (HIV) protease inhibitor therapy on lipoprotein production and catabolism in vivo. The HIV protease inhibitor ritonavir was given to C57BL/6 mice fed either a basal low-fat diet or a Western ...
Tara M. Riddle, Nicholas M. Schildmeyer, Cam Phan, Carl J. Fichtenbaum, David Y. Hui   +4 more
doaj   +1 more source

ALDH2 rs671 and MTHFR rs1801133 polymorphisms are risk factors for arteriosclerosis in multiple arteries

BMC Cardiovascular Disorders, 2023
Background Arteriosclerosis in multiple arteries has long been associated with heightened cardiovascular risk. Acetaldehyde dehydrogenase 2 (ALDH2) and methylenetetrahydrofolate reductase (MTHFR) play an important role in the pathogenesis of ...
Nan Cai, Cunren Li, Xianfang Gu, Wenfeng Zeng, Jingfeng Liu, Guopeng Zeng, Jiawei Zhong, Junxing Zhu, Haifeng Hong   +8 more
doaj   +1 more source

Association between total bilirubin and gender-specific incidence of fundus arteriosclerosis in a Chinese population: a retrospective cohort study

Scientific Reports, 2023
To investigate the gender-specific relationship between total bilirubin (TBIL) and fundus arteriosclerosis in the general population, and to explore whether there is a dose–response relationship between them.
Yongfei Dong, Chunxing Liu, Jieli Wang, Huijun Li, Qi Wang, Aicheng Feng, Zaixiang Tang   +6 more
doaj   +1 more source

A nomogram based on radiomics intermuscular adipose analysis to indicate arteriosclerosis in patients with newly diagnosed type 2 diabetes

Frontiers in Endocrinology, 2023
ObjectiveEarly identifying arteriosclerosis in newly diagnosed type 2 diabetes (T2D) patients could contribute to choosing proper subjects for early prevention.
Cong He, Dong Xie, Lin-feng Fu, Jin-na Yu, Fang-ye Wu, Yong-gang Qiu, Hong-wei Xu   +6 more
doaj   +1 more source

Differential expression of ACAT1 and ACAT2 among cells within liver, intestine, kidney, and adrenal of nonhuman primates

Journal of Lipid Research, 2000
Two closely related enzymes with more than 50% sequence identity have been identified that catalyze the esterification of cholesterol using acyl-CoA substrates, namely acyl-CoA:cholesterol acyltransferase 1 (ACAT1) and ACAT2.
Richard G. Lee, Mark C. Willingham, Matthew A. Davis, Kelly A. Skinner, Lawrence L. Rudel   +4 more
doaj   +1 more source