Results 31 to 40 of about 57,345 (140)

The role of phosphatidylserine recognition receptors in multiple biological functions

Cellular & Molecular Biology Letters, 2020
Apoptotic cells are rapidly engulfed and degraded by phagocytes through efferocytosis. Efferocytosis is a highly regulated process. It is triggered upon the activation of caspase-dependent apoptosis, which in turn promotes the expression of “eat me ...
Mehri Bemani Naeini, Vanessa Bianconi, Matteo Pirro, Amirhossein Sahebkar   +3 more
doaj   +1 more source

Individual assessment of arteriosclerosis by empiric clinical profiling. [PDF]

PLoS ONE, 2007
BACKGROUND: Arteriosclerosis is a common cause of chronic morbidity and mortality. Myocardial infarction, stroke or other cardiovascular events identify vulnerable patients who suffer from symptomatic arteriosclerosis.
Marcus Mutschelknauss, Marco Kummer, Juergen Muser, Steve B Feinstein, Peter M Meyer, Barbara C Biedermann   +5 more
doaj   +1 more source

Global DNA methylation mediates the association between serum perfluorooctane sulfonate and carotid intima-media thickness in young and middle-aged Taiwanese populations

Ecotoxicology and Environmental Safety, 2022
Purpose: Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are a group of synthetic chemicals used in the manufacture of many everyday products. Previous reports have shown PFAS exposure may contribute to cardiovascular diseases (CVD).
Chien-Yu Lin, Hui-Ling Lee, Ching-Way Chen, Chikang Wang, Fung-Chang Sung, Ta-Chen Su   +5 more
doaj   +1 more source

SR-B1, a Key Receptor Involved in the Progression of Cardiovascular Disease: A Perspective from Mice and Human Genetic Studies

Biomedicines, 2021
High plasma level of low-density lipoprotein (LDL) is the main driver of the initiation and progression of cardiovascular disease (CVD). Nevertheless, high-density lipoprotein (HDL) is considered an anti-atherogenic lipoprotein due to its role in reverse
Irene Gracia-Rubio, César Martín, Fernando Civeira, Ana Cenarro   +3 more
doaj   +1 more source

Studies on the effect of dietary fish oil on the physical and chemical properties of low density lipoproteins in cynomolgus monkeys.

Journal of Lipid Research, 1991
To determine the effect of isocaloric substitution of dietary fish oil for lard on the physical and chemical properties of plasma low density lipoproteins (LDL), ten adult male cynomolgus monkeys were fed diets containing 11% (by weight) fish oil or lard
JS Parks, AK Gebre
doaj   +1 more source

Identification of ACAT1- and ACAT2-specific inhibitors using a novel, cell-based fluorescence assay

Journal of Lipid Research, 2004
Acyl CoA:cholesterol acyltransferase 1 (ACAT1) and ACAT2 are enzymes responsible for the formation of cholesteryl esters in tissues. While both ACAT1 and ACAT2 are present in the liver and intestine, the cells containing either enzyme within these ...
Aaron T. Lada, Matthew Davis, Carol Kent, James Chapman, Hiroshi Tomoda, Satoshi Omura, Lawrence L. Rudel   +6 more
doaj   +1 more source

Validation of a microRNA profile in urine liquid biopsy with diagnostic and stratification value for bladder cancer classification, available through the open app BladdermiRaCan

Experimental Hematology & Oncology
We aimed to identify a profile of urine microRNAs (miRNAs) with diagnostic and stratification potential in the whole range of bladder cancer (BC) categories, to avoid current invasive, harmful and expensive procedures.
Julia Oto, Raquel Herranz, Emma Plana, Javier Pérez-Ardavín, David Hervás, Fernando Cana, Patricia Verger, David Ramos-Soler, Manuel Martínez-Sarmiento, César D. Vera-Donoso, Pilar Medina   +10 more
doaj   +1 more source

Decreased level of serum carnitine might lead to arteriosclerosis progression via the accumulation of advanced glycation end products in maintenance hemodialysis patients

Renal Replacement Therapy, 2017
Background Carnitine is reported to improve insulin resistance and reduce oxidative stress. Hyperglycemia and increased oxidative stress are well known to promote the production of advanced glycation end products (AGEs) that can lead to arteriosclerosis ...
Yumi Kamada, Takashi Masuda, Kazuhiko Kotani, Shinya Tanaka, Takeshi Nakamura, Nobuaki Hamazaki, Yoko Itoh, Ibuki Moriguchi, Naoyuki Kobayashi, Michihito Okubo, Kazuhiro Takeuchi, Shokichi Naito, Yasuo Takeuchi   +12 more
doaj   +1 more source

Association between obstructive sleep apnea hypopnea syndrome and arteriosclerosis in patients with type 2 diabetes mellitus: mediating effect of blood pressure

Frontiers in Endocrinology
ObjectiveThis study aims to explore the relationship between Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) and arteriosclerosis in type 2 diabetes mellitus (T2DM) patients and to evaluate the mediating effect of blood pressure in this process ...
Xinshui Wang, Xiaolin Huang, Yuexian Xing, Xiaohong Jiang, Fei Hua   +4 more
doaj   +1 more source

Association between Plasma Adipocytokines Levels and Intracranial versus Extracranial Atherosclerotic among Chinese Patients with Stroke

Iranian Journal of Public Health, 2020
Background: To detect the levels of plasma Adipocytokines, TNF-α, IL-6 and PAI-1 in patients with intracranial and extracranial arteriosclerosis. Methods: From September 2015 to September 2017, 318 patients aged ≥60 years were enrolled.
Chunyu LIU, Xiaodan YANG, Changqing CHEN
doaj