Construction of prediction models for novel subtypes in patients with arteriosclerosis obliterans undergoing endovascular therapy: an unsupervised machine learning study [PDF]
Journal of Cardiothoracic SurgeryBackground Arteriosclerosis obliterans (ASO) is a chronic arterial disease that can lead to critical limb ischemia. Endovascular therapy is increasingly used for limb salvage in ASO patients, but the outcomes vary.
Xiaocheng Li +4 more
doaj +3 more sources
Loss of GRB2 associated binding protein 1 in arteriosclerosis obliterans promotes host autophagy [PDF]
Chinese Medical Journal, 2021 . Background:. Arteriosclerosis obliterans (ASO) is a major cause of adult limb loss worldwide. Autophagy of vascular endothelial cell (VEC) contributes to the ASO progression. However, the molecular mechanism that controls VEC autophagy remains unclear.
Meng Ye +10 more
doaj +3 more sources
Increased Level of Tim-3+PD-1+CD4+T Cells With Altered Function Might Be Associated With Lower Extremity Arteriosclerosis Obliterans [PDF]
Frontiers in Immunology, 2022 Lower extremity arteriosclerosis obliterans (LEASO) is a vascular disease that may result in adult limb loss worldwide. CD4+T cell-mediated immunity plays a significant role in LEASO.
Liyuan Cui +6 more
doaj +3 more sources
Expression and clinical significance of HSP27 and its phosphorylation in lower extremity arteriosclerosis obliterans [PDF]
PeerJ, 2020 Objectives This study set out to analyze the difference of heat shock protein 27 (HSP27) and its phosphorylation in patients with lower extremity arteriosclerosis obliterans (LEASO) at different stages.
Junqing Bai +7 more
doaj +4 more sources
Novel Insight Into Long-Term Risk of Major Adverse Cardiovascular and Cerebrovascular Events Following Lower Extremity Arteriosclerosis Obliterans [PDF]
Frontiers in Cardiovascular Medicine, 2022 BackgroundPatients with lower extremity arteriosclerosis obliterans (LEASO) are more likely to appear to be associated with adverse cardiovascular outcomes.
Ji Sun +14 more
doaj +3 more sources
Construction and validation of a nomogram model for predicting the risk of recurrence in patients with lower extremity arteriosclerosis obliterans after surgical intervention [PDF]
Journal of Cardiothoracic SurgeryObjective To explore and analyze the risk factors for recurrence in patients with lower extremity arteriosclerosis obliterans (ASO) after surgical intervention and to construct and validate a nomogram prediction model.
Yanyan Lu +3 more
doaj +3 more sources
Ameliorative effects of the traditional Chinese medicine formula Qing-Mai-Yin on arteriosclerosis obliterans in a rabbit model [PDF]
Pharmaceutical Biology, 2020 Context Qing-Mai-Yin (QMY) is a clinically used herbal formula for treating arteriosclerosis obliterans (ASO). Objective To evaluate the chemical constituents and effects of QMY on ASO rabbit model.
Lei Zhang +7 more
doaj +3 more sources
MicroRNA-30a-3p: a potential noncoding RNA target for the treatment of arteriosclerosis obliterans [PDF]
Aging (Albany NY), 2023 An increasing number of studies have shown that noncoding RNAs are involved in cardiovascular diseases. Our study shows that the expression of microRNA-30a-3p (miR-30a-3p) in patients with arteriosclerosis obliterans (ASO) of the lower extremities is ...
Mao Zhang +5 more
semanticscholar +2 more sources
Association Between Thromboelastography and Coagulation for Disease Severity Evaluation in Patients With Lower Extremity Arteriosclerosis Obliterans [PDF]
J Clin Lab AnalThis study confirmed a significant correlation between TEG and coagulation function. Elevated FIB and D‐D levels combine with increased MA and α‐angle of TEG to determine systemic hypercoagulation status and thrombosis risks. The application of TEG and coagulation indices provides a more rapid and intuitive supplementary means for early monitoring of ...
Zhen Huang +5 more
europepmc +3 more sources
Relationship between Angiotensin II, Vascular Endothelial Growth Factor, and Arteriosclerosis Obliterans [PDF]
Dis Markers, 2023 Objective To investigate the relationship between angiotensin II (Ang II), vascular endothelial growth factor (VEGF), and arteriosclerosis obliterans (ASO).
Yulian Liu +5 more
semanticscholar +2 more sources