Results 51 to 60 of about 42,170 (187)

Specific Enhancement of Vascular Endothelial Growth Factor (VEGF) Production in Ischemic Region by Alprostadil — Potential Therapeutic Application in Pharmaceutical Regenerative Medicine

Journal of Pharmacological Sciences, 2013
Alprostadil (lipo-PGE1) is a drug delivery system preparation. This preparation is applied to treat refractory skin ulcers and arteriosclerosis obliterans. We investigated the effects of alprostadil by using the earflap ischemic model.
Hajime Inoue, Masaki Aihara, Miyuki Tomioka, Yu-ichi Watabe   +3 more
doaj   +1 more source

Importance of inflammation in arteriosclerotic plaque destabilization and rupture [PDF]

Vojnosanitetski Pregled, 2005
Introduction. Although Rudolf Virchow considered arteriosclerosis an inflammatory disease in his book Cellular Pathology published in 1858, the opinion that it was a degenerative arterial disease as a civilization disease prevailed.
Tatić Vujadin, Kanjuh Vladimir, Rafajlovski Saša I., Kostić Kristina, Šuščević Dušan   +4 more
doaj   +1 more source

A prospective, multicenter, real-world observational study evaluating the impact of tibial runoff on clinical outcomes after endovascular therapy for femoropopliteal lesions: Research protocol

Frontiers in Cardiovascular Medicine, 2022
IntroductionCurrent evidence indicates endovascular intervention is a safe and effective treatment for peripheral artery disease of the lower extremity. However, the clinical outcome of endovascular intervention for femoropopliteal lesions has been shown
Yang Liu, Qiqi Wang, Ziheng Wu, Zibo Fen, Lianrui Guo, Qiang Li, Xin Fang, Hongfei Sang, Yudi Dai, Chunshui He, Meng Ye   +10 more
doaj   +1 more source

Therapeutic Effects of Interventional Therapy and Conservative Therapy on Lower Extremity Arteriosclerosis Obliterans and Risk Factors for Prognosis

Artery Research, 2021
Arteriosclerosis Obliterans (ASO) is an important cause for lower limb amputation. We aimed to compare the effects of interventional and conservative therapies on lower extremity ASO, and to analyze the risk factors for prognosis.
Lingxiong Chen, Xuming Zhang, Fuyan Jiang, Zhida Yin, Ji-ke Xue, Chengmei Ruan, Lijiao Xie   +6 more
semanticscholar   +1 more source

Activation of monocytes and cytokine production in patients with peripheral atherosclerosis obliterans

Journal of Inflammation, 2011
Background Arterial peripheral disease is a condition caused by the blocked blood flow resulting from arterial cholesterol deposits within the arms, legs and aorta. Studies have shown that macrophages in atherosclerotic plaque are highly activated, which
Lastória Sidney, Calvi Sueli A, Dias-Melicio Luciane A, Corrêa Camila R, Soares Angela MVC   +4 more
doaj   +1 more source

TREATMENT OF ARTERIOSCLEROSIS OBLITERANS WITH PYRIDINOLCARBAMATE

Nihon Naika Gakkai Zasshi, 1967
75例の閉塞性動脈硬化症例にpyridinolcarbamate治療を試みた結果,つぎの結論に達した. 1) Double blind法による38症例(pyridinolcarbamate群19, placebo群19)の2週間治療の結果, pyridinolcarbamateは本症に対して有効であることがわかつた. 2) 75例(男70,女5)についての1カ月から23カ月にわたる長期治療により,つぎの結果が得られた,すなわち,有効例は53例(71%)で,動脈拍動の改善は75例中26例に,知覚異常の改善は23例12例に,間歇性跛行の改善は47例中26例にみられた.またcyanosisの消失, ruborの軽減,潰瘍の治癒率はそれぞれ30, 27, 81%であり ...
ATSUMI, Toshiyuki, ISOKANE, Noriko, YAMASHITA, Sekiya, SANO, Tadahiro, ODAKURA, Tsutomu, KURAI, Akira   +5 more
openaire   +3 more sources

Application of Big Data Deep Learning in Auxiliary Diagnosis of Lower Extremity Arteriosclerosis Obliterans

Journal of Clinical and Nursing Research, 2021
At present, the incidence rate of arteriosclerosis obliterans (LEASO) of the lower extremities is significantly increased by aging and lifestyle changes.
Linbo Liu, Yang Liu, Hongjun Wang, Yi Zhang, Zhijie Liao, Shendong Du   +5 more
semanticscholar   +1 more source

Quantitative Measurement of Extracellular Vesicle‐Sized Particles in Blood Plasma by Laser Diffraction Without an Extraction Process: A Proof‐of‐Concept Study in Atrial Fibrillation

Journal of Arrhythmia, Volume 42, Issue 3, June 2026.
Laser diffraction enabled rapid measurement of extracellular vesicle‐sized particles in fasting plasma without an extraction process. In this proof‐of‐concept study, particle concentrations were higher in atrial fibrillation than in controls, suggesting the potential of this simple approach for biomarker assessment.
Giichi Nitta, Kotone Tatsumi, Nurjahon Ummatalieva, Suzuka Ishikawa, Satomi Hamada, Anna Suzuki, Rina Iwasaki, Kohei Kawajiri, Ryutaro Kobayashi, Junji Yamaguchi, Ryunosuke Ohkawa, Kotaro Yoshioka, Tetsuya Nagata, Takanori Yokota, Kensuke Ihara, Tetsuo Sasano   +15 more
wiley   +1 more source

Current Status and Associated Factors of Discharge Readiness in Lower Extremity Peripheral Artery Disease Patients: A Cross‐Sectional Study

The Journal of Clinical Hypertension, Volume 28, Issue 6, June 2026.
ABSTRACT This study investigated the current readiness for hospital discharge (RHD) among patients with lower extremity peripheral arterial disease (PAD) following endovascular revascularization within an enhanced recovery after surgery (ERAS) model and analyzed its associated factors.
Yaqing Wang, Yaqiong Li, Bihui Zhang, Junmei Li   +3 more
wiley   +1 more source

Two Cases of Kounis Syndrome Caused by Contrast Medium: Early Extracorporeal Membrane Oxygenation

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT In cardiology, Kounis syndrome (KS), also known as allergic angina or myocardial infarction, is often overlooked in emergencies. Its pathophysiology differs from that of allergic reactions such as anaphylaxis, making differentiation essential.
Kiichi Yano, Yu Asami, Takumi Inoue, Emiko Takego, Kenji Tamai, Hiroyuki Takahashi   +5 more
wiley   +1 more source